本篇論文主要分成了五個章節，分別是前言、實驗目標、實驗結果與討論、結論及實驗步驟。前言介紹異噁唑啉衍生物在有機合成和藥物化學的領域具有重要的發展性及，並且透過查詢近幾年的文獻來回顧有關於異噁唑啉衍生物的合成方法。
實驗目標及實驗結果與討論是將起始物2-烯丙氧基-3-甲氧基苯甲醛肟，利用超音波震盪器，藉由不同的醇類作為有機溶劑和碘分子進行分子內[3+2]環化加成反應，並以良好的產率成功合成出具有三環骨架結構的產物6-Methoxy-3a, 4-dihydro-3H-chromeno[4,3-c]isoxazole。

This thesis has five parts including introduction, experimental objectives, experimental results, conclusion, and experimental procedure. The preface introduces the important development of isoxazoline derivatives in the field of organic synthesis and medicinal chemistry, and reviews the synthesis methods of isoxazoline derivatives by searching the literature in recent years.
Experimental objectives, experimental results and discussion introduce intramolecular [3+2] cycloaddition of 2-allyloxy-3-methoxybenzaldoxime which is starting material by using ultrasonic cleaner and different alcohols as organic solvents and iodine molecules, and successfully synthesized the product 6-Methoxy-3a, 4-dihydro-3H-chromeno[4,3-c]isoxazole which has tricyclic skeleton structure in good yields.

1. J. I Andres, J Alc ´ azar, J. M. Alonso, ´ R. M. Alvarez, M. H. Bakker, I Biesmans, J. M. Cid, A. I. D. Lucas, W. Drinkenburg, J Fernandez, L. M. Font, L. Iturrino, X. Langlois, ´ I. Lenaerts, S. Martı’nez, A. A. Megens, J Pastor, S. Pullan and T. Steckler, Bioorg. Med. Chem., 2007, 15, 3649
2. James W. Shearman, Rebecca M. Myers, James D. Brenton, Steven V. Ley , Org. Biomol. Chem. 2011, 9, 62
3. Beugnet F, deVos C, Liebenberg J, Halos L, Fourie J. Afoxolaner against fleas: immediate efficacy and resultant mortality after short exposure on dogs. Parasite. 2014, 21, 42
4. I. Filali, J. Bouajila, M. Znati, F. Bousejra-El Garah, H. Ben Jannet, J. Enzyme. Inhib. Med. Chem. 2015, 30, 371-376
5. Easton, C. J.; Hughes, C. M. M.; Savage, G. P.; Simpson, G. W. Adv. Heterocycl. Chem. 1994, 60, 261
6. Huisgen, Rolf (October 1963). "1,3-Dipolar Cycloadditions. Past and Future". Angewandte Chemie International Edition in English. 2 (10): 565–598.
7. Radhakrishna, A. S.; Sivaprakash, K.; Singh, B. B. Synth. Commun. 1991, 21, 1625
8. Das, B.; Holla, H.; Mahender, G.; Banerjee, J.; Reddy, M. R. Tetrahedron Lett. 2004, 45, 7347
9. Das, B.; Holla, H.; Mahender, G.; Venkateswarlu, K.; Bandgar, B. P. Synthesis 2005, 1572
10. Chatterjee, N.; Pandit, P.; Halder, S.; Patra, A.; Maiti, D. K. J. Org. Chem. 2008, 73, 7775
11. Raihan, M. J.; Kavala, V.; Kuo, C.-W.; Raju, R.; Yao, C.-F. Green Chem. 2010, 12, 1090
12. Minakata, S.; Okumura, S.; Nagamachi, T.; Takeda, Y. Org. Lett. 2011, 13, 2966,
13. Yoshimura, A.; Middleton, K. R.; Todora, A. D.; Kastern, B. J.; Koski, S. R.; Maskaev, A. V.; Zhdankin, V. V. Org. Lett. 2013, 15, 4010
14. Yoshimura, A.; Zhu, C.; Middleton, K. R.; Todora, A. D.; Kastern, B. J.; Maskaev, A. V.; Zhdankin, V. V. Chem. Commun. 2013, 49, 4800
15. Han, L.; Zhang, B.; Xiang, C.; Yan, J. Synthesis 2014, 46, 503