簡易檢索 / 詳目顯示

研究生: 黃筠庭
Huang Yun Ting
論文名稱: 利用由情緒圖片刺激所產生的伴隨性腦磁波形變化研究受測者放鬆程度
A study of the relaxing by analyzing the contingent magnetic variations in MEG via the stimulus of affective pictures
指導教授: 洪姮娥
Horng, Herng-Er
楊鴻昌
Yang, Hong-Chang
學位類別: 碩士
Master
系所名稱: 光電工程研究所
Graduate Institute of Electro-Optical Engineering
論文出版年: 2012
畢業學年度: 100
語文別: 中文
論文頁數: 44
中文關鍵詞: 腦磁圖
論文種類: 學術論文
相關次數: 點閱:54下載:0
分享至:
查詢本校圖書館目錄 查詢臺灣博碩士論文知識加值系統 勘誤回報
  • 先前研究指出,伴隨性負電位變化(Contingent negative variation,CNV)之振幅,對於個體的心理狀態是有效的量測指標。故本研究將利用低溫超導量子干涉元件(Superconducting Quantum Interference Device,SQUID)組成之128通道腦磁圖儀(Magnetoencephalography,MEG)系統,來深入探討由情緒圖片刺激所造成人體放鬆狀態下的腦磁訊號。藉由觀察磁場的等位線分佈圖(magnetic isofield contour map)及電流密度(Current Density Reconstruction,CDR)推算腦磁訊號源的結果,來分析不同情緒圖片下所對應到大腦皮質層反應區域的差異。
    受試者共五位身體健康符合實驗需求的受試者來參加實驗。本研究實驗設計採用情緒圖片來產生心理放鬆程度的不同,以進行腦磁波的量測。結果顯示左半腦運動區之CMV振幅大小會隨著圖片不愉快的程度增加而上升,雖然每位個體對於不同的情緒圖片刺激在CMV波幅上會產生有不一樣的活躍程度,但每一位受試者於觀看愉悅圖片時與不愉悅圖片時的CMV波幅在統計上有顯著差異,所以運動區之CMV振幅用來量測情緒狀態是非常有效的量測指標。

    摘要 1 目錄 2 1. 緒論 3 1.1 腦磁圖研究 3 1.2 伴隨性誘發磁場變化(CMV) 5 2. 研究動機與實驗方法 8 2.1 研究動機 8 2.2 腦磁圖儀系統 9 2.3 受測者 10 2.4 受試者頭部座標的標定 11 2.5 實驗刺激之材料 16 2.6 CMV之腦磁訊號的量測 18 3. 數據分析與結果討論 20 3.1 CMV發生時活化的腦部區域---------------------------------------20 3.2 情緒圖片對CMV波幅變化的影響-------------------------------34 參考文獻 40 附錄一 愛丁堡慣用手量表 42 附錄二 刺激圖片之情緒量表 43

    1. Y H Lee, K.K.Y., H Kwon, J M Kim, K Kim, Y K Park, H C Yang, K L Chen, S Y Yang and H E Horng, A whole-head magnetoencephalography system with compact axial gradiometer structure. Superconductor Science and Technology, 2009. 22(4).
    2. al, M.H.e., Magnetoencephalography – theory, instrumentation, and applications to noninvasive studies of the working human brain. . Reviews of modern physics, 1993. 65: p. 413-493.
    3. Kuen-Lin Chen, H.-C.Y., Sung-Ying Tsai, Yu-Wei Liu, Shu-Hsien Liao, Herng-Er Horng, Yong-Ho Lee, and Hyukchan Kwon, The stability of source localization in a whole-head magnetoencephalography system demonstrated by auditory evoked field measurements. Journal of Applied Physics 2011. 110(7).
    4. Walter, W.G., et al., Contingent Negative Variation: An Electric Sign of Sensorimotor Association and Expectancy in the Human Brain. Nature, 1964. 203: p. 380-4.
    5. Frost, J.D., Jr., P. Kellaway, and A. Gol, Single-unit discharges in isolated cerebral cortex. Exp Neurol, 1966. 14(3): p. 305-16.
    6. Tecce, J.J., Contingent negative variation (CNV) and psychological processes in man. Psychol Bull, 1972. 77(2): p. 73-108.
    7. McCallum, W.C. and W.G. Walter, The differential effects of distraction on the contingent negative variation in normal subjects and psychiatric patients. Electroencephalogr Clin Neurophysiol, 1968. 24(6): p. 593.
    8. Elbert, T., et al., The magnetic counterpart of the contingent negative variation. Electroencephalogr Clin Neurophysiol, 1994. 92(3): p. 262-72.
    9. N'Diaye, K., L. Garnero, and V. Pouthas, Contingent negative/magnetic variation during time perception: Simultaneous MEG and EEG recordings. Journal of Psychophysiology, 2003. 17(1): p. 56-56.
    10. Stanley, J. and R.G. Knight, Emotional specificity of startle potentiation during the early stages of picture viewing. Psychophysiology, 2004. 41(6): p. 935-40.
    11. Hariri, A.R., et al., The amygdala response to emotional stimuli: a comparison of faces and scenes. Neuroimage, 2002. 17(1): p. 317-23.
    12. Northoff, G., et al., Functional dissociation between medial and lateral prefrontal cortical spatiotemporal activation in negative and positive emotions: a combined fMRI/MEG study. Cereb Cortex, 2000. 10(1): p. 93-107.
    13. Hariri, A.R., et al., Neocortical modulation of the amygdala response to fearful stimuli. Biol Psychiatry, 2003. 53(6): p. 494-501.
    14. Lang, P.J., et al., Emotional arousal and activation of the visual cortex: an fMRI analysis. Psychophysiology, 1998. 35(2): p. 199-210.
    15. Wagner, M., Köhler, Thomas, Wischmann,Linear and Nonlinear Current Density Reconstructions Fuchs. Journal of Clinical Neurophysiology. 16: p. 267-295.
    16. R.D., P.-M., Standardized low resolution brain electromagnetic tomography (sLORETA): technical detail. Meth. Findings Exp. Clin. Pharmacol, 2002. 24: p. 5-12.
    17. Gomez, C.M., et al., Task-specific sensory and motor preparatory activation revealed by contingent magnetic variation. Brain Res Cogn Brain Res, 2004. 21(1): p. 59-68.
    18. Hansenne, M. and M. Ansseau, Contingent negative variation and personality in depression. Neuropsychobiology, 2001. 44(1): p. 7-12.
    19. Mantanus, H., et al., [Relationship between dexamethasone suppression test and contingent negative variation in major depressive patients]. Neurophysiol Clin, 1988. 18(4): p. 345-53.
    20. Timsit-Berthier, M., et al., Contingent negative variation in major depressive patients. Electroencephalogr Clin Neurophysiol Suppl, 1987. 40: p. 762-71.

    無法下載圖示 本全文未授權公開
    QR CODE