大腦在自主運動上扮演著非常重要的角色。本研究利用128通道全腦式腦磁圖儀來探討人類自主手指按鍵運動與想像手指按鍵運動大腦神經元活化的差異性。本論文之實驗分為兩個階段，第一階段為自主手指按鍵實驗，第二階段為想像手指按鍵實驗，主要想比較這兩種實驗大腦活化之差異性。總共有9位受試者參與本次試驗，我們將受試者進行手指按鍵運動所產生的動作關聯皮質磁場(Movement- related cortical fields, MRCFs)以及想像手指按鍵運動的訊號用腦磁圖紀錄下來。
我們採用CURRY 6.0這套腦波分析軟體對運動神經元的位置進行定位。在自主手指按鍵實驗數據分析上，我們先使用軟體計算出動作關聯皮質磁場 (MRCFs)在每一個時刻的mean global field power (MGFP)，然後選取MGFP的最大值，再統計出所有受試者左手與右手實際按鍵運動動作關聯皮質磁場 (MRCFs)延遲時間。首先我們針對全腦作分析，結果顯示右手與左手實際按鍵運動動作關聯皮質磁場(MRCFs)平均延遲時間之間並無顯著差異。之後我們將某位受試者的數據分為左、右半腦做更精確的分析，發現同側半腦並無明顯特徵波形，但對側腦確有明顯特徵波形。因此我們針對對側腦動作關聯皮質磁場 (MRCFs)延遲時間做分析，最後比較右、左手手指按鍵運動全腦與對側腦各特徵波形的延遲時間，發現不論是全腦還是對側腦，各特徵波形的延遲時間均相同，證實了手指運動這個動作是由對側腦控制。
進一步分析我們利用電流密度重建方法建立各受試者的大腦模型，比較兩階段實驗運動特徵波形活化位置以及活化程度，實際運動的活化區域為precentral gyrus (中央前迴)、postcentral gyrus (中央後迴)。想像運動的活化區域為superior parietal lobule (上頂葉)、inferior parietal lobule (下頂葉)、precentral gyrus (中央前迴)、postcentral gyrus (中央後迴)、cerebullum (小腦)、premotor cortex (運動前皮質)及insula(腦島)。我們發現實際運動及想像運動的活化區域具有差異。

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