背景：本研究的目的在探討運動前攝取咖啡因與碳水化合物對阻力運動後能量代謝與同化性荷爾蒙反應的影響。方法：本研究的受試者為10名有規律阻力運動習慣的男性大學生。所有受試者在實驗前接受最大肌力 (1RM) 測驗後，以平衡次序分配進行攝取咖啡因 (CAF；6mg/kg)、碳水化合物 (CHO；1g/kg)、咖啡因＋碳水化合物 (CHO＋CAF；1g+6mg/kg) 與安慰劑 (CON) 等4次實驗，每次實驗間隔7天，受試者在阻力運動開始前1小時攝取增補劑，隨後進行阻力運動 (3組；75%1RM強度進行10次反覆；8個動作；每組休息時間為5分鐘)。在運動前1小時 (pre-60)、運動前立即 (pre-exe) 與運動後0、15、30分鐘 (P0、P15、P30) 抽取血液。本研究以相依樣本二因子 (實驗處理×時間) 變異數分析 (ANOVA) 檢定內分泌反應 (睪固酮、生長激素、皮質固醇、胰島素) 與能量代謝指標 (血糖、血乳酸、游離脂肪酸) 在不同實驗處理下是否有顯著差異。結果：數據分析後發現CHO在阻力運動後生長激素 (P0) 與胰島素 (P0、P15) 的濃度顯著提升，睪固酮 (P0、P15、P30) 和皮質固醇的濃度 (P0、P15) 顯著降低 (p< .05)，CAF在阻力運動後生長激素的濃度 (P0、P15、P30) 顯著降低 (p< .05)，CHO＋CAF顯著提升阻力運動後胰島素濃度 (P0)，降低睪固酮濃度 (P0、P15、P30) (p< .05)。結論：1.阻力運動前攝取葡萄糖提升運動後生長激素與胰島素的反應，降低血液中睪固酮濃度，並且抑制皮質固醇的分泌。2.攝取咖啡因降低運動後生長激素的反應，但對胰島素、睪固酮與皮質固醇沒有顯著影響。3.同時攝取咖啡因與葡萄糖提升運動後胰島素的反應與降低血液中睪固酮濃度，但對生長激素與皮質固醇並沒有顯著影響。因此，咖啡因的攝取可能會降低葡萄糖對阻力運動後同化性荷爾蒙分泌環境的影響。

Background: The purpose of this study was to investigate the effects of caffeine and carbohydrate intake on substrate metabolism and acute hormonal responses to a single bout of resistance exercise (RE). Methods: Ten university male students regularly perform RE participated in this study. All subjects performed 1RM test, then performed four treatments:caffeine (CAF, 6mg/kg), carbohydrate (CHO, 1g/kg), carbohydrate+caffeine (CHO＋CAF, 1g+6mg/kg) and control (CON) in counter balance order. All subjects intaked supplement 1 hour prior RE, then, the subjects performed RE (eight exercises, 3 sets of 10 repetitions at 75% of 1RM). Blood samples collected prior supplement intake (pre-60), immediately prior RE (pre-exe), and 0, 15, 30 min after RE (P0, P15, P30) for analysis of testosterone, cortisol, growth hormone, insulin, glucose, free fatty acid and lactic acid. Each experiment separated by 7 days. In this study, statistical analysis of a two-way analysis of variance (treatment by time) with repeated measures was applied. Results: After RE, CHO’s response of GH (P0) and insulin (P0, P15) were significantly higher than CON, the response of testosterone (P0, P15, P30) and cortisol (P0, P15) were significantly lower than CON (p<.05). CAF's response of GH (P0, P15, P30) was significantly lower than CON (p< .05). CHO＋CAF’s response of insulin (P0) was significantly higher than CON, the response of testosterone (P0, P15, P30) was significantly lower than CON (p<.05). Conclusion: The results of this study indicated that intake glucose prior RE increased the response of GH and insulin, decreased the concentration of testosterone and cortisol. Moreover, intake caffeine prior RE inhibited the response of GH. Intake glouse and caffeine prior RE raise the response of insulin and decreased the concentration of testosterone, but no significant effects on GH and cortisol.

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