當歸、川芎為常用之中藥，兩者藥效與植物均相似，在中藥處方中常同時
使用。皆含有精油、胺基酸、脂肪酸、有機酸、醣類等成份；具鎮靜、解
痙、抗炎、降血壓等作用。本研究以有機酸、精油成份為指標，利用高效
液相層析儀分析臺灣種植之大和當歸在不同時期、各部位的含量；並分析
比較市售當歸、川芎藥材的差異。分析結果顯示:臺灣種植之大和當歸中
ligustilide 含量在花(6.98 mg/g)與果實(8.49 mg/g)中、
butylidenephthalide 含量在果實(0.59 mg/g)中、ferulic acid 含量在
開花前的葉片(0.25 mg/g)中含量最多。市售當歸藥材中含有 nicotinic
acid(0-0.57 mg/g)、phthalic acid(0.01-0.34 mg/g)、folic
acid(0-0.58 mg/g)、vanillic acid(0.05-0.09 mg/g)、ferulic
acid(0.23-0.76 mg/g)、but-ylidenephthalide(0.06-1.53 mg/g)、
ligustilide(6.90-24.95 mg/g)、butylphthalide(0.36-3.08 mg/g)。市
售川芎藥材中含有 nicotinic acid(0-0.42 mg/g)、protocatechuic
acid(0.01-0.37 mg/g)、phthal-ic acid(0.09-0.50 mg/g)、folic
acid(0-0.52 mg/g)、p-hydroxybenzoic acid(0-0.03 mg/g)、vanillic
acid(0.06-0.20 mg/g)、caffeic acid(0.01-0.23 mg/g)、ferulic
acid(0.41-1.10 mg/g)、butylphthalide(0.04-0.97 mg/g)、
senkyunolide A(0.80-3.70 mg/g)、ligustilide(6.20-14.06 mg/g)、
butylidenephthalide (3.11-5.74 mg/g)。可利用 senkyunolide A 的有
無來區別當歸與川芎。原則上當歸藥材以頭部粗、歸身粗、切面色澤白、
香氣濃郁者較佳；川芎藥材以藥材大、切面色澤白、香氣濃郁者較佳。

Angelicae Radix and Ligustici are two commonly used Chinese
herbal drugs. They have similar constituents and
pharmacological activities, and are used together in many
Chinese herbal preparations. It is found that the drugs possess
sedative, antispasmodic, antiinflammatory and blood level
decreasive effects and contain essential oils, amino acids,
fatty acids, orangic acids and carbohydrates. In this study, we
used orangic acids and essential oils as indexing standard to
investigate the differences between samples of different growing
times and different parts from the plants of Angelica acutiloba
Kitagawa grown in Taiwain by high-performance liquid
chromatography. The quality of commercial Angelicae Radix and
Ligustici Rhizoma has also been studied by this method.The
analytical data showed that the highest contents of the
individual components were that ligustilide in flowers(6.98 mg/
g) and fruit(8.49 mg/g), butylidenephthalide in fruit(0.59 mg/g)
and ferulic acid in leaves(0.25 mg/g) before blooming. The
contents of commercial Angelicae Radix were as follows:
nicotinic acid 0-0.57 mg/g, phthalic acid 0.01-0.34 mg/g, folic
acid 0-0.58 mg/g, vanillic acid 0.05-0.09 mg/g, ferulic acid
0.23-0.76 mg/g, butylidenephthalide 0.06-1.53 mg/g, ligustilide
6.90-24.95 mg/g and butylphthalide 0.36-3.08 mg/g. The contents
of commerical Ligustici Rhizoma were as follows: nicotinic acid
0-0.42 mg/g, protocatechuic acid 0.01-0.37 mg/g, phthalic acid
0.09-0.50 mg/g, folic acid 0-0.52 mg/g, p-hydroxybenzoic acid
0-0.03 mg/g, vanillic acid 0.06-0.20 mg/g, caffeic acid
0.01-0.23 mg/g, ferulic acid 0.41-1.10 mg/g, butylphthalide
0.04-0.97 mg/g, senkyunolide A 0.80-3.70 mg/g, ligustilide
6.20-14.06 mg/g and butylidenep-hthalide 3.11-5.74 mg/g.As a
result, the presence of senkyunolide A can be used to
distinguish Angilicae Radix from Ligustici Rhizoma and the
external appearance can be used to predict the quality of the
drugs.
Angelicae Radix and Ligustici are two commonly used Chinese