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1
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Down-regulation of ribose-5-phosphate isomerase attenuates Tau mediated toxicity in Drosophila
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Department of Life Science
/103/ Doctor
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Author:
Hsin-Chieh Shiau
Advisor:
Su, Ming-Tsan
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Tauopathy is a multifactorial disease in which many pathogenic pathways have been identified thro...
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Clicks: 204
Downloads: 1
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2
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Functionnal Characterization of a Novel gene ,Him , in Heart Development of Drosophila
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Department of Life Science
/92/ Master
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Author:
Yong-Siang Lin
Advisor:
Su, Ming-Tsan
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Abstract
During animal embryogenesis, heart is the first funtional organ to be formed. Heart pro...
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Clicks: 367
Downloads: 5
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3
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蛋白質磷酸酶2A次單元-Twins 調控果蠅肌動蛋白質動態之研究
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Department of Life Science
/96/ Master
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Author:
Tzu-Wei Lin
Advisor:
Su, Ming-Tsan
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蛋白質磷酸酶2A是為一廣泛表現的serine -threonine磷酸酶，參與許多細胞內重要的基本功能如：有絲分裂、細胞凋亡和細胞形態發生。本研究的主要目的，為探討蛋白質磷酸酶2A對細胞肌動蛋白...
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Clicks: 248
Downloads: 0
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4
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Loss of TBP function causes apoptosis due to oxidative stress and p53 activation in Drosophila melanogaster
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Department of Life Science
/101/ Master
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Author:
Chin-Sern Yong
Advisor:
Su, Ming-Tsan
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Previous studies revealed that loss of TBP function causes developmental arrest and apoptosis in ...
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Clicks: 265
Downloads: 1
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5
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TBP deactivation contributes to amyloid mediated toxicity in a Drosophila model of Alzheimer’s disease
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Department of Life Science
/103/ Master
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Author:
Jian-Wen Zheng
Advisor:
Su, Ming-Tsan
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Protein aggregation is a pathological hallmark of many neurodegenerative diseases, including Alzh...
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Clicks: 176
Downloads: 10
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6
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Functional Characterization of Bb Regulatory Subunit of PP2A in Mitochondrial Remodeling and Apoptosis Using Drosophila as a Model
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Department of Life Science
/98/ Master
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Author:
Yu-Chun Wang
Advisor:
Su, Ming-Tsan
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Spinal cerebellar ataxia type 12 (SCA12) has been attributed to the elevated expression of ppp2r2...
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Clicks: 287
Downloads: 8
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7
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Development of therapeutic small molecule drugs targeting BDNF receptor TRKB for the treatment of neurodegenerative diseases-AD Drosophila models
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Department of Life Science
/107/ Master
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Author:
Wu, Bo-Yi
Advisor:
Su, Ming–Tsan
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The extracellular β-amyloid (Aβ) forming plaques and Tau containing intraneuronal neurofibrillary...
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Clicks: 270
Downloads: 3
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8
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Functional Study of twins, the Drosophila PP2A B Subunit and it’s Interaction with Tau
 This full text is not authorized to be published.
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Department of Life Science
/98/ Doctor
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Author:
Po-An Yeh
Advisor:
Su, Ming-Tsan
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Misregulated PR55Bβ, a B regulatory subunit of protein phosphotase 2A (PP2A), has long been docum...
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Clicks: 225
Downloads: 0
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9
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Down-regulation of histone deacetylase attenuates Tau neurotoxicity in Drosophila
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Department of Life Science
/103/ Master
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Author:
黃昱嘉
Advisor:
Su, Ming-Tsan
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Tau is a neuronal enriched protein whose function is to stabilize the structure of microtubules, ...
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Clicks: 170
Downloads: 1
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10
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Dysfunction of TBP contributes to the pathogenesis of tauopathy
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Department of Life Science
/100/ Master
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Author:
Hsiang-Yu Wang
Advisor:
Su, Ming-Tsan
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Previous studies found that the TATA box-binding protein (TBP) is sequestered by tau-mediated neu...
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Clicks: 242
Downloads: 1
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