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1
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Single-molecule Fluorescence Resonance Energy Transfer spectroscopy Study on the Conformational Interconversion Kinetics of Human Telomere G-quadruplexes Influenced by Local Chemical Environment
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Department of Chemistry
/104/ Master
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Author:
Hsu, Hao-Yi
Advisor:
Lee, I-Ren
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G-quagruplexes, secondary structures formed by guanine-rich DNA sequences in the telomere regions...
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Clicks: 136
Downloads: 8
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2
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Influence of Trinucleotide Repeat Sequences to the SSB Loading and Redistribution
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Department of Chemistry
/107/ Master
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Author:
Huang, Kun-Kai
Advisor:
Lee, I-Ren
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Trinucleotide repeat (TNR) expansions are responsible for many neurodegenerative disorders. TNRs ...
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Clicks: 177
Downloads: 0
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3
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Single-Molecule Study on the Retardation of DNA Slipping Motions in Error-Prone Tandem DNA Repeats Using Echinomycin and a Small-molecule Drug
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Department of Chemistry
/106/ Master
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Author:
Wei, Yu-Jie
Advisor:
Lee, I-Ren
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Expansion of trinucleotide repeats (TNRs) was responsible for many genetic disorders, and the for...
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Clicks: 155
Downloads: 1
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4
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Salt concentration dependence on DNA hairpin conformational dynamics of CAG and CTG repeats associated with neurodegenerative diseases
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Department of Chemistry
/108/ Master
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Author:
Wang, Hong-Ren
Advisor:
Lee, I-Ren
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Trinucleotide repeat (TNR) is responsible for several neurodegenerative diseases. Among them, CAG...
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Clicks: 190
Downloads: 11
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5
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Interconversion between G-quadruplex Conformations in B-cell Lymphoma 2 Promoter Region
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Department of Chemistry
/106/ Master
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Author:
Chen, Chiao-Ying
Advisor:
Lee, I-Ren
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B-cell Lymphoma 2 (Bcl-2) is a proto-oncogene that is responsible for cell apoptosis. The overexp...
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Clicks: 149
Downloads: 2
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6
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Structural Dynamics Study of B-cell Lymphoma Oncogene G-quadruplex Molecules Using Single-Molecule Spectroscopy
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Department of Chemistry
/104/ Master
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Author:
Wu, Jia-Yu
Advisor:
Lee, I-Ren
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B-cell lymphoma 2 (Bcl-2) is an oncoprotein that involves in the regulation of programmed cell de...
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Clicks: 146
Downloads: 10
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7
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Structural and Kinetics Study on the Tandem Repeats of TGGAA Sequences Associated with Spinocerebellar Ataxia Type 31 Disease
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Department of Chemistry
/104/ Master
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Author:
Chin, Chih-Hao
Advisor:
Lee, I-Ren
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Spinocerebellar ataxia 31 (SCA31) is a neurodegenerative hereditary disease, mainly popular in Ja...
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Clicks: 168
Downloads: 7
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8
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Real-time Observation of DNA Slippage Motions in Tandem CTG Repeats Using Single-molecule Spectroscopy.
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Department of Chemistry
/105/ Master
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Author:
Ni, Cheng-Wei
Advisor:
Lee, I-Ren
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Tandem nucleotide repeats are responsible for many genetic neurodegenerative disorders. Among the...
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Clicks: 156
Downloads: 9
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9
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Structural Kinetics of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Linked GGGGCC Repeats Studied by Single-Molecule Fluorescence Resonance Energy Transfer
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Department of Chemistry
/106/ Master
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Author:
Ting, Chien-Chi
Advisor:
Lee, I-Ren
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Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are severe neurodegenerativ...
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Clicks: 196
Downloads: 33
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10
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Single-Molecule Study on the Conformational Dynamics of d(CGG) Tandem Repeats Associated with Fragile X Syndrome and Their Disease Inhibition Mutations
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Department of Chemistry
/106/ Master
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Author:
Shen, Yang-I
Advisor:
Lee, I-Ren
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The expansion of CGG/CCG trinucleotides in the fragile X mental retardation (FMR1) gene leads to ...
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Clicks: 139
Downloads: 1
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