中文摘要
第一部分
本部分包含一章，闡述了路易斯酸介導的炔酮和1-萘酚的環化反應。
第 1 章：“通過 BF3.Et2O 介導的 1-萘酚和 Ynones 的一鍋級聯 4,5-環化反應合成 Perinaphthenones”
我們提供了一種簡單而獨特的方法，用於使用 α-萘酚與 ynone 的 C4-C5 環環化反應合成高度取代的環萘酮。我們使用現成的起始材料在 30 分鐘內在 C4-C5 位點完成了 1-萘酚的脫芳香環環化，收率從良好到中等。此外，所提出的程序不僅可以替代前述方法，而且還可以簡單地合成迄今為止難以獲得的 4,6-二芳基環萘酮衍生物。我們還注意到新創建的化合物是發光的。

關鍵詞：環萘酮；圍產期; α-萘酚；伊諾內斯；無溶劑。 

第二部分
本部分闡述了α-溴烯胺酮的合成及其應用
第 2 章：“3-溴丙烯醛與苯胺反應合成 α-溴烯胺酮的研究”
使用一鍋法描述了-溴烯胺酮的合成。不需要外部溴化劑，因為反應由對甲苯磺酸一水合物 (TsOH.H2O) 介導的 3-溴丙烯醛與苯胺在二甲亞砜 (DMSO) 中的反應催化。在鄰位連接有空間位阻吸電子基團的苯胺用於進行化學選擇性1,2-加成。此外，使用額外的苯胺衍生物作為親核試劑的反應產生了少量的 1,4-加成產物。對於苯胺衍生物，3-溴丙烯醛表現出廣泛的反應性。

關鍵詞：一鍋法合成； α-溴烯胺酮；3 溴丙烯醛；苯胺；二甲基亞砜。

第三部分

本部分包含通過溶劑捕獲異納扎羅夫中間體合成環戊烯稠合衍生物。

第 3 章：“碘介導的與乙腈/丙酮的間斷 Iso-Nazarov 反應用於獲得高度取代的環戊烯稠合衍生物。”

我們實現了前所未有的碘介導溶劑捕獲的共軛二烯底物異納扎羅夫反應，以產生非對映選擇性環戊烯稠合衍生物。目前的方法是第一個捕獲共軛二烯醛在乙腈/丙酮中的異納扎羅夫反應中產生的環戊氧基烯丙基陽離子。

關鍵詞: 異納扎羅夫, 乙腈, 丙酮,

PART-I
This part contains one chapter, which illustrates the Lewis acid mediated annulation reaction of ynones and 1-naphthols.
CHAPTER-1: “Synthesis of Perinaphthenones via BF3.Et2O 4,5-Annulation Reactions of 1-Naphthols and Ynones”
We provide a simple and unique approach for the synthesis of highly substituted perinaphthenones using C4-C5 peri-annulation reactions of α-napthols with ynones. We accomplished dearomative peri-annulation of 1-napthols at C4-C5 sites in 30 minutes using readily available starting materials with yields ranging from good to moderate. Furthermore, the proposed procedure would not only be an alternative to the previously stated methods, but it would also allow for the simple synthesis of heretofore difficult to get 4,6-diarylperinaphthenone derivatives. We also noticed that the newly created compounds were luminous.
This part illustrates the synthesis of α-Bromo Enaminones and their applications
CHAPTER-2: “A Study of the Reactions of 3-Bromopropenals with Anilines for the Synthesis of α-Bromo Enaminones”
The synthesis of -bromo enaminones is described using a one-pot method. There is no need for an external brominating agent because the reactions are catalyzed by p-toluenesulfonic acid monohydrate (TsOH.H2O) mediated reactions of 3-bromopropenals with anilines in dimethyl sulfoxide (DMSO). Aniline with a sterically hindered electron-withdrawing group attached at the ortho-position was used to perform the chemoselective 1,2-addition. Furthermore, reactions employing additional aniline derivatives as nucleophiles yielded small yields of the 1,4-addition product. With aniline derivatives, the 3-bromopropenals displayed a wide spectrum of reactivities.
Part III
This part contains synthesis of cyclopentene fused derivatives from trapping of iso-Nazarov intermediate by solvents.

CHAPTER-3: “Iodine mediated interrupted Iso-Nazarov reaction with Acetonitrile/Acetone for Accessing Highly Substituted Cyclopentene fused derivatives.”

We achieved an unprecedented iodine-mediated solvent trapped iso-Nazarov reaction of conjugated dienal substrate to produce diastereoselective cyclopentene fused derivatives. The current approach is the first to capture the cyclopentyl oxyallyl cation produced in the iso-Nazarov reaction of conjugated dienals in acetonitrile/acetone.

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