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研究生: 林志韋
Lin, Chih-Wei
論文名稱: 用於光學同調斷層掃描之基於深度學習和聯邦學習框架之視網膜積液分割技術
Retinal Fluid Segmentation Technology Based on Deep Learning and Federated Learning Framework for Optical coherence tomography
指導教授: 呂成凱
Lu, Cheng-Kai
口試委員: 呂成凱
Lu, Cheng-Kai
連中岳
Lien, Chung-Yueh
林承鴻
Lin, Cheng-Hung
口試日期: 2024/07/15
學位類別: 碩士
Master
系所名稱: 電機工程學系
Department of Electrical Engineering
論文出版年: 2024
畢業學年度: 112
語文別: 中文
論文頁數: 93
中文關鍵詞: 視網膜積液分割深度學習卷積神經網路聯邦學習
英文關鍵詞: Retinal Fluid Segmentation, Deep learning, Convolutional Neural Network, Federated Learning
研究方法: 實驗設計法準實驗設計法
DOI URL: http://doi.org/10.6345/NTNU202401376
論文種類: 學術論文
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在眼科領域,光學相干斷層掃描(OCT)是檢測眼病的關鍵技術。偏鄉資源有限僅能使用輕量化設備,但其計算能力不足,難以支撐較為大型模型的訓練,以及數據缺乏和隱私問題阻礙醫院數據共享。首先針對輕量化設備,基於LEDNet設計了高效的LEDNet(α)模型,通過調整通道、添加Shuffle Attention模塊和Group Normalization。使用成本低廉的樹莓派5進行訓練,適合偏鄉需求,為解決隱私問題,引入聯邦學習,通過上傳本地模型參數聚合全局模型,避免資料直接上傳。本研究提出Krum(α)算法,在客戶端損失函數中添加近端項並考慮模型自適應性,改善淘汰機制,改進基於歐氏距離淘汰惡意模型的Krum算法。最後實驗結果顯示,在AROI、DUKE、UMN和RETOUCH數據集上,AROI積液類別提高了3.4%,DUKE提高了5.9%,UMN提高了2.4%,RETOUCH提高了1.4%。

In the field of ophthalmology, Optical Coherence Tomography (OCT) is a key technology for detecting eye diseases. In resource-limited rural areas, only lightweight devices can be used, but it’s computational power is insufficient to support the training of large models. Additionally, data scarcity and privacy issues hinder data sharing between hospitals. First, for lightweight devices, an efficient LEDNet(α) model was designed based on LEDNet by adjusting channels, adding Shuffle Attention modules, and using Group Normalization. Training was conducted using the low-cost Raspberry Pi 5, suitable for rural needs. To solve privacy issues, federated learning was introduced, aggregating a global model by uploading local model parameters, avoiding direct data upload. This study proposes the Krum(α) algorithm, improving the Krum algorithm based on Euclidean distance by adding a proximal term in the client's loss function and considering model adaptability, improving the elimination mechanism. Finally, experimental results showed that on the AROI, DUKE, UMN, and RETOUCH datasets, the AROI exudate category improved by 3.4%, DUKE by 5.9%, UMN by 2.4%, and RETOUCH by 1.4%.

第一章 緒論 1 1.1 背景和研究動機 1 1.2 研究目標 4 1.3 研究範圍與限制 4 1.4 論文貢獻 5 1.5論文架構 6 第二章 文獻探討 7 2.1 光學相干斷層掃描 7 2.2 電腦輔助診斷法 9 2.2.1 基於CNN的方法 10 2.3 聯邦學習 19 2.3.1 聯邦學習基礎框架 19 2.3.2 聯邦學習分類 20 2.3.3 聯邦學習資料非獨立同分布 25 2.3.4 聯邦學習演算法發展及平台 27 第三章 研究方法設計 33 3.1 研究流程 33 3.2 資料集 36 3.2.1 AROI Dataset 36 3.2.2 DUKE Dataset 39 3.2.3 UMN Dataset 39 3.2.4 Retouch Dataset 39 3.3 LEDNet(α)模型架構 40 3.3.1 LEDNet 40 3.3.2 LEDNet(α) 45 3.4 聯邦學習架構 53 3.4.1 架構的選擇 53 3.4.2 Krum(α) 53 3.5 效能標準 57 3.5.1 參數量(Parameters) 57 3.5.2 浮點數計算運算次數(FLOPs) 58 3.5.3 運算強度 59 3.6 評估標準 61 第四章 實驗結果與討論 63 4.1 實驗說明 63 4.2 實驗環境 67 4.2.1 硬體規格表 67 4.2.2 軟體環境 68 4.3 研究結果 69 4.3.1 實際佈署 69 4.3.2 AROI資料集 70 4.3.3 DUKE資料集 72 4.3.4 UMN資料集 75 4.3.5 RETOUCH 資料集 78 4.3.6 模型運算強度比較 80 4.4 消融實驗 82 第五章 結果與未來展望 84 5.1 結論 84 5.2 未來展望 85 參考文獻 86 自 傳 92 學術成就 93

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