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研究生: 李欣怡
論文名稱: 低磁場之核磁共振
指導教授: 楊鴻昌
Yang, Hong-Chang
洪姮娥
Horng, Herng-Er
學位類別: 碩士
Master
系所名稱: 光電工程研究所
Graduate Institute of Electro-Optical Engineering
論文出版年: 2009
畢業學年度: 97
語文別: 中文
論文頁數: 51
中文關鍵詞: 核磁共振低磁場
論文種類: 學術論文
相關次數: 點閱:203下載:0
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  • 低磁場之核磁共振比起高磁場之核磁共振,磁場均勻度要求較低,線圈建造成本較低,且訊號不受化學位移影響,可觀察化合物之分子特性。在實驗室環境下進行低磁場之核磁共振量測 ( NMR ),以 0.74 Tesla 之釹鐵硼磁鐵做為預磁化場,來增加樣品之磁化量,使 NMR 訊號辨識度提高。量測在不同主磁場下的 NMR 訊號,觀察主磁場的不均勻度對 FID 訊號之影響,藉以找出最適當之主磁場。利用核磁共振量測量含有 J-coupling 訊號之化合物,如:三甲基磷酸與三氟乙醇,觀察其原子核自旋交互作用對 NMR 訊號的影響。磁流體為一磁性粒子,將其加入水中量測會影響水的磁場不均勻度,因此我們量測不同濃度磁流體的水核磁共振訊號,由量測結果觀察不同濃度磁流體與自旋自旋弛緩時間 ( T2 ) 關係。

    目錄 第一章 緒論.......................................1 1.1 低磁場核磁共振簡介............................1 1.2 核磁共振原理..................................3 第二章 實驗架構...................................11 2.1 低磁場核磁共振系統設計........................11 2.2 訊號量測......................................15 2.3 訊號處理方法..................................18 第三章 實驗結果與數據討論.........................20 3.1 不同主磁場(B0)之訊號量測......................20 3.2 J-coupling...................................23 3.3 含不同磁流體濃度之水的T2量測..................30 第四章 結論.......................................43 參考文獻..........................................45 致謝..............................................51

    1. P.T. Callaghan, M. Legros, “Nuclear spins in the Earth’s magnetic
    field, “Am. J. Phys. 50 ,709 (1982)
    2. Bene GJ, 4 Int. S. Magn. Res. Reh. (1971).
    3. G.J. Bene, “Nuclear magnetism of liquid-systems in the Earth’s field
    range”, Phys. Rep. 58,213 (1980).
    4. P.T. Callaghan, C.D. Eccles, J.D. Seymour, “An Earth’s field nuclear
    magnetic resonance apparatus suitable for pulsed gradient spin echo
    measurements of self-diffusion under Antarctic conditions”, Rev. Sci.
    Instrum. 68, 4263 (1997)
    5. P.T. Callaghan, C.D. Eccles, T.G. Haskell, P.J. Langhorne, J.D.
    Seymour, “Earth’s field NMR in Antarctica: a pulsed gradient spin
    echo NMR study of restricted diffusion in sea ice”, J. Magn.
    Reson.133, 148 (1998).
    6. P.T. Callaghan, R. Dykstra, C.D. Eccles, T.G. Haskell, J.D. Seymour,
    “A nuclear magnetic resonance study of Antarctic sea ice brine
    diffusivity”, Cold Reg. Sci. Technol. 29 ,153 (1999)
    7. O.R. Mercier, M.W. Hunter, P.T. Callaghan, “Brine diffusion in
    firstyear sea ice measured by Earth’s field PGSE-NMR”, Cold Reg.
    Sci.Technol. 42, 96 (2005).
    8. J.S. Brown Robert, “Earth’s field nuclear magnetic logging”,
    Concept.Magnetic Res. 13, 344 (2001).
    9. S. Appelt, F. W. Hasing, H. Kuhn, U. Sieling, and B. Blumich,”
    Analysis of molecular structures by homo- and hetero-nuclear
    J-coupled NMR in ultra-low field”. Chem. Phys. Lett. 440, 308
    (2007)
    10. S. Appelt, A. Ben-Amar Baranga, C.J. Erickson, M.V. Romalis,
    A.R.Young, W. Happer, ”Theory of spin-exchange optical pumping
    of 3He and 129Xe “, Phys. Rev. A 58, 1412 (1998).
    11. M. Goldman, H. Jo’hannesson, O. Axelsson, M. Karlsson,
    “Hyperpolarization of 13C through order transfer from parahydrogen:
    A new contrast agent for MRI “, Magn.Reson. Imaging 23,153
    (2005) .
    12. G. Navon, Y.-Q. Song, T. Ro˜o˜m, S. Appelt, R.E. Taylor, A. Pines,”
    Enhancement of Solution NMR and MRI with Laser-Polarized
    Xenon”, Science 271, 1848 (1996).
    13. S. Appelt, F.W. Ha‥sing, S. Baer-Lang, N.J. Shah, B. Blümich,
    “Enhancement of Solution NMR and MRI with Laser-Polarized
    Xenon”, Chem.Phys. Lett. 348, 263 (2001)
    14. Hong-Chang Yang, Shu-Hsien Liao and Herng-Er Horng, and
    Shing-Ling Kuo, Hsin-Hsien Chen, and Shieh-Yueh Yang,
    “Enhancement of nuclear magnetic resonance in microtesla magnetic
    field with prepolarization field detected with high-Tc
    superconducting quantum interference device”, Appl. Phys. Lett. 88,
    252505(2006)
    15. Shu-Hsien Liao and Herng-Er Horng, Hong-Chang Yang, and
    Shieh-Yueh Yang, “Longitudinal relaxation time detection using a
    high-Tc superconductive quantum interference device magnetmeter”,
    J. Appl. Phys. 102, 033914 (2007).
    16. M.A. Espy, A.N. Matlachov, P.L. Volegov, J.C. Mosher, and R.H.
    Kraus Jr., ” SQUID-Based Simultaneous Detection of NMR and
    Biomagnetic Signals at Ultra-Low Magnetic Fields”, IEEE Trans.
    Appl. Supercon. 15, 635 (2005).
    17. A.H. Trabesinger, R. McDermott, S.K. Lee, M. Mu1ck, J. Clarke,
    and A. Pines , “ SQUID-Detected Liquid State NMR in Microtesla
    Fields“, J. Phys. Chem. A, 108, 957-963 (2004).
    18. R. McDermott, S.K. Lee, B. ten Haken, A.H. Trabesinger, A. Pines,
    and J. Clarke, “Microtesla MRI with a superconducting quantum
    interference Device”, Proc. Natl. Acad. Sci. USA , 101, 7857 (2004).
    19. M. Mössle, S. Busch, M. Hatridge, W. Myers, A. Pines, and J. Clarke,
    “SQUID-detected microtesla MRI: a new modality for tumor
    detection”, paper presented at 2006 Applied Superconductivity
    conference, Aug. 27-Sept.1, 2006, Seattle, Washington, USA.
    20. A.E. Derome, "NMR Techniques for Chemistry Research",
    Pergamon Press, NY 1987.
    21. Atta-ur-Rahman, "Nuclear Magnetic Resonance, Basic Principles",
    Springer-Verlag, NY 1986.
    22. Brend Seeber, Handbook of Applied Superconductivity
    23. W.G. Proctor, F.C. Yu, “On the Nuclear Magnetic Moments of
    Several Stable Isotopes “, Phys. Rev. 81, 20 (1951).
    24. W.G. Proctor, F.C. Yu, “The Dependence of a Nuclear Magnetic
    Resonance Frequency upon Chemical Compound “, Phys. Rev. 77,
    717 (1950)
    25. R. Freeman, A Handbook of Nuclear Magnetic Resonance, Longman
    Scientific & Technical, Essex, England, (1988).
    26. Medek, L. Frydman, “Multiple - Quantum Magic - Angle Spinning
    NMR: A New Technique for Probing Quadrupolar Nuclei in Solids”,
    J. Braz. Chem. Soc. 10, 263(1999)
    27. M A Bernstein, K F King and X J Zhou. Handbook of MRI Pulse
    Sequences. Elsevier Academic Press, 960 (2004)
    28. Zhi-Pei Liang and Paul C. Lauterbur, ”Principles of Mageetic
    Resonance Imaging: A Signal Processing Perspective”.
    29. Sasada and Y. Nakashima, “Planar coil system consisting of three coil
    pairs for producing a uniform magnetic field”, J. Appl. Phys. 99,
    08D904 (2006)
    30. S. Appelt, H. Kühn, F. W. Häsing, and B. Blümich, “Chemical
    analysis by ultrahigh-resolution nuclear magnetic resonance in the
    Earth’s magnetic field”, Nat. Phys. 2, 105 (2006)
    31. Longqing Qiu, Yi Zhang, Hans-Joachim Krause, and Alex I.
    Braginski, “Nuclear magnetic resonance in the earth’s magnetic field
    using a nitrogen-cooled superconducting quantum interference
    device”, Appl. Phys. Lett. 91,072505 (2007)
    32. Robert McDermott, Andreas H. Trabesinger, John Clarke,”
    Liquid-State NMR and Scalar Couplings in Microtesla Magnetic
    Fields”, Science, 295,2247 (2002)
    33. Shu-Hsien Liao , Hong-Chang Yang ,Herng-Er Horng and S Y Yang, ”Characterization of magnetic nanoparticles as contrast agents in magnetic resonance imaging using high-Tc superconducting quantum interference devices in microtesla manetic fields”,Supercond.Sui.Technol.22 025003 (2009)
    34. Hui Dong, Yongliang Wang, Shulin Zhang, Yue Sun and Xiaoming Xie,”Detection of proton NMR signal in the Earth’s magnetic field at an urban laboratory environment without shielding”, Supercond. Sci. Technol. 21 115009 (2008)

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