在本研究中利用極性的冠狀醚－羧酸雙苯16冠5 (sym-dibenzo-16-
crown-5-oxyacetic acid, DB16C5~COOH) 和碳簇分子－碳六十(C60)，成
功地合成出一種冠狀醚-碳六十複合物(DB16C5~COOC60)，並將其塗佈在石
英晶片電極膜上，做為石英壓電晶體偵測器（piezo-electric quartz
crystal detector），並且應用在於離子層析儀上；石英晶體振盪器的石
英膜表面，會因吸附離子或分子化合物，而使負載之重量增加，造成石英
晶體振盪頻率隨之遞減，再透過自製微電腦介面中的頻率-電壓(F/V)轉換
器，將振盪頻率轉換成類比電壓訊號，再經類比/數位轉換器轉成數位訊
號，輸出至電腦做數據處理。 本研究中所研製出的冠狀醚-碳六十液
體層析石英壓電晶體膜感測器，對離子化合物偵測的線性範圍是從0.1Ｍ
～5×10-4Ｍ，而偵測極限分別為(1)鹼金屬離子約為3×10-3Ｍ(1.5
×10-5mmole)；(2)鹼土金屬離子約為5×10-4Ｍ(2.5×10-6mmole)；(3)
過渡金屬離子約為1×10-3Ｍ(5×10-6mmole)；不同的離子其偵測極限亦
有所不同，IIA族鹼土金屬離子＞過渡金屬離子＞IA族鹼金屬離子，此與
離子的直徑大小和價數有關。 本研究之碳六十-冠狀醚石英壓電偵測
器，除了對金屬離子化合物有好的再現性和靈敏度之外，對於有機離子以
及有機分子、溶劑亦有良好的偵測結果；在極性有機分子方面，以胺類的
吸附感應最好，為胺類＞有機酸＞醇類＞＞酮類；而在非極性有機分子方
面，分別偵測單鍵、雙鍵以及三鍵之己烷、己烯和己炔，結果本研究之碳
六十-冠狀醚石英壓電偵測器對炔類的偵測感應最好，為炔類＞＞烯類＞
烷類，此乃因為本研究合成之複合物，有類似缺電子的碳六十那端與多電
子之缺類產生吸附力所致。 本研究之碳六十-冠狀醚石英壓電偵測器
，同時與商業上所使用的導電度計，在穩定性與再現性方面，都擁有良好
的競爭性。

Fullerene ( C60 )-crown ether ( sym-dibenzo-16-
crown-5-oxyacetic acid ) derivative ( DB16C5~COOC60 ) was
prepared , and DB16C5~ COOC60 derivative coated piezoelectric
quartz crystal membrane detector for ion chromatograph with a
microcomputer interface for signal processing was designed to
detect various organic ions and metal ions in solution .
The C60-crown ether piezoelectric quartz detector exhibited high
sensitivity for the change of its surface weight , the C60-crown
ether quartz crystal membrane showed adsorptive ability to
adsorb various ions in ion chromatography . Mean while , the
mass increase of quartz crystal surface membranes caused the
decrease in oscillating frequency of quartz, and the variations
of the crystal frequencies were converted to voltage with a
frequency to voltage converter , and followed by amplification
with OPA and data acqusition with an analog to digital converter
. The C60-crown ether piezoelectric quartz detector was
applied to detect various ions such as alkali metal , alkaline
earth metal and transition metal ions with detection limits
between 5×10-4 M ~ 1×10-3 M . The detection limits were
3×10-3 M (1.5×10-5 mmole) , 5×10-4 M (2.5×10-6 mmole) and
1×10-3 M (5×10-6 mmole) for alkali metal , alkaline earth
metal and transition metal ions respectively. The ionic sizes
and ionic charges seemed to give some significant effect on the
detection limits of these ions. The crown ether - C60
piezoelectric quartz detector was also emlpoyed to detect
various organic polar molecules such as amines, alcohols ,
carboxylic acids and ketones ,and the piezoelectric quartz
detector's responses were in the order : amine ＞ carboxylic
acid ＞ alcohol ＞ ketones ( R-NH2 ＞ R-COOH ＞ R-OH ＞ acetone
) . In addition , nonpolar organic molecules such as n-hexane ,
1-hexene anf 1-hexyne were also detected with the C60 - crown
ether piezoelectric quartz detectorand their detection responses
were in the order : 1-hexyne ＞＞ 1-hexene ＞ n-hexane .
The piezoelectric quartz detector showed quite good sensitivity
, short response time ( < 1 min ) and good reproducibility . The
C60- crown ether piezoelectric quartz detector demonstrated
competitive responses as a commercial conductivity detector
conventionally used in ion chromato-graphy.
Fullerene ( C60 )-crown ether ( sym-dibenzo-16-