一連串由三牙配子N-3,5-取代基-，N-3,4-苯并-和N-5,6-苯并-亞柳胺基酸所衍生之氧釩(IV)錯合物，可以有效分別扮演各式3-,6-,7-取代-α酚氧化偶合反應，我們針對催化劑的各種製備方法與特性，偶合反應中溶劑與共氧化劑效應，各種α-胺基酸光輔劑的效應，與催化反應機構深入作探討，在許多酚衍生物氧化偶合反應中，我們發展出的催化劑所獲得的鏡像選擇性均比文獻已知方法為高，且此類錯合物穩定性高，製備容易且經濟，是極具價值的研究課題，其中我們以2-羥基-1-苯并柳醛 和2-胺基異戊酸（或苯丙胺酸）所衍生而成的氧釩 (IV)錯合物為催化劑，可以得到1,1’-雙-萘酚產率75~100%，和高達62%的鏡像選擇性，亦是已知非對稱催化方法中最成功的，其初步的研究結果在此發表。

A series of chiral oxovanadium(IV) complexes derived from tridentate N-3,5-substituted and N-3,4-benzo- and N-5,6-benzo-salicylidene-α-amino acids can serve as efficient catalysts for the enantioselective oxidative couplings of various 3-,6-,7-substituted- 2-naphthols under O2. We take the reseach about the solvent effect,cooxidant effect,amino acid effect….and so on in detail. Our catalyst in the coupling reaction of 2-naphthol is the best methodology as we know. The best scenario involves the use of a vanadyl complex arising from 2-hydroxy-1-naphtholaldehyde and valine (or phenylalanine) in CCl4, leading to BINOLs in good yields (75-100%) and with enantioselectivities of up to 68%.

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