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研究生： 李佳倫
Chia-Lun Lee
論文名稱： 短期增補羥基檸檬酸對耐力性運動表現之影響
Effect of short-term (-)-hydroxycitric acid supplementation on endurance exercise performance
指導教授： 林正常
Lin, Jung-Charng
學位類別： 碩士
Master
系所名稱： 體育學系
Department of Physical Education
論文出版年： 2005
畢業學年度： 93
語文別： 中文
論文頁數： 84
中文關鍵詞： 羥基檸檬酸 、耐力性運動表現 、身體組成 、呼吸交換率
英文關鍵詞： (-)-hydroxycitric acid, endurance exercise performance, body composition, respiratory exchange rate
論文種類： 學術論文
相關次數： 點閱：274  下載：16 
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    • 目的：探討短期增補羥基檸檬酸對耐力運動表現的影響。方法： 17名健康男性自願參加以單盲為設計的實驗，且經由隨機分配為兩組：H組（羥基檸檬酸，2.5g/day，n=9，年齡：21.7±2.4歲，身高：177.9±6.4 cm，體重：67.4±5.9 kg）與P組（纖維素，2.5g/day，n=8，年齡：21.7±1.7歲，身高：173.3±4.2 cm，體重：66.6±7.7 kg）。連續五天增補羥基檸檬酸之前後，所有受試者須在原地跑步機上完成遞增負荷之耐力性運動測驗。遞增耐力性運動包括10分鐘的低強度（40%VO2max）與10分鐘的高強度（80%VO2max）運動，且隨後以每3分鐘增加2%坡度的負荷直到運動衰竭，並利用生物電阻法分析受試者身體組成的各項數據。結果：羥基檸檬酸組的體脂肪比增補前顯著降低（p < .05），而肌肉重與去脂體重則明顯比增補前增加（p < .05）。不論是在低強度或高強度下或增補前與增補後，羥基檸檬酸組與安慰劑組之間的心跳率、每分鐘攝氧量和運動後血乳酸值均無顯著差異存在（p > .05），然而，羥基檸檬酸組在低強度時的呼吸交換率與碳水化合物顯著降低，脂肪氧化顯著增加（p < .05），且衰竭時間也顯著地延長（p <.05）。結論：短期增補羥基檸檬酸不會影響低強度或高強度運動時的心跳率、每分鐘攝氧量與血乳酸值，儘管如此，羥基檸檬酸有助於促進脂肪氧化與延緩運動衰竭的時間。

    Purpose: To investigate the effect of short-term (-)-hydroxycitric acid (HCA) supplementation on endurance exercise performance. Methods: Seventeen healthy males volunteered to participate in this single blind study, and were randomly divided in two groups: H group (HCA, 2.5 g/day, n = 9, age: 21.7±2.4 yrs, height: 177.9±6.4 cm, weight: 67.4±5.9 kg) and P group (cellulose, 2.5 g/day, n = 8, age: 21.7±1.7 yrs, height: 173.3±4.2 cm, weight: 66.6±7.7 kg). Before and after a 5-day load of HCA or placebo, all subjects performed an incremental endurance exercise test. The incremental endurance exercise test included 10-min mild (40%VO2max) and 10-min heavy (80%VO2max) exercises and then the slope of treadmill was increased two degrees every three minutes till volitional exhaustion. Body composition was measured by bioelectrical impedance analyzer. Results: There was a significantly decreased body fat only in H group (p < .05), and the lean body mass and muscle mass were significantly increased in H group after supplementation (p < .05). The heart rate (HR), oxygen intake and blood lactate had no significant differences between the H and P groups (p > .05), however, in the H group, the respiratory exchange rate (RER) and carbohydrate (CHO) oxidation were significantly decreased, and the fat oxidation was significantly increased (p < .05) during mild endurance exercise. In addition, the exhausting time was significantly extended in the H group (p < .05). Conclusion: Short-term HCA supplementation could not affect HR, oxygen intake and blood lactate either on the mild or the heavy endurance exercise, however, the fat oxidation and time to exhaustion during the endurance exercise would be improved by HCA.

    口試委員與系主任簽字證書……………………………….. I 授權書…………………………………………………….. II 中文摘要………………………………………………………….. IV 英文摘要………………………………………………………….. V 謝誌…………………………………………………………….. VI 目次………………………………...................... VII 表次…………………………………...................... IX 圖次……………………………….......................... X 第壹章 緒論 第一節 前言...………………………………………… 1 第二節 問題背景...………………………………………….. 2 第三節 研究的重要性……………………………………... 5 第四節 研究目的………………………………………….. 6 第五節 研究範圍…………………………………….. 6 第六節 研究限制……………………...……………………... 7 第七節 操作性定義...………………………………………… 7 第貳章 文獻探討 第一節 增補羥基檸檬酸對減重之影響...…………………... 10 第二節 羥基檸檬酸對運動表現之影響...………………….. 22 第三節 本章總結……………………...………………………. 26 第參章 方法 第一節 受試對象……………………………………....…. 28 第二節 實驗設計…………………………………...……… 28 第三節 實驗日期…………………………………...………… 29 第四節 實驗地點……………………………………........................ 29 第五節 實驗流程…………………………………...........................29 第六節 實驗方法與步驟……………………………........ 31 第七節 資料處理與分析…………………………….......... 36 第肆章 結果 第一節 受試者基本資料……………………………….. 38 第二節 生理反應……………………………………….. 38 第三節 耐力性運動表現…………….................. 46 第伍章 討論與結論 第一節 生理反應…………………………………….......... 47 第二節 耐力性運動表現…………….................... 55 第三節 結論與建議……………………………….................... 56 引用文獻………………………………………….............. 58 附錄一 受試者須知……………………………………………… 63 附錄二 受試者健康調查表…………….……………………… 64 附錄三 受試者自願同意書……………………………………...66 附錄四 實驗紀錄表……………………………….............................67 附錄五 受試者基本資料表……………………………………. 70 附錄六 受試者之耐力性運動與最大攝氧量資料表…………… 71 附錄七 受試者之身體組成資料表……………………………… 72 附錄八 受試者之血乳酸值與耐力性運動表現資料表………….73 附錄九 受試者之心跳率、每分鐘攝氧量與最大心跳率資料表 74 附錄十 受試者之呼吸交換率、碳水化合物與脂肪氧化資料表 75 附錄十一 所得結果之變異數分析摘要表……………………… 76 表一 受試者基本資料表…………………………..................................38 表二-1 總體重變異數分析摘要表..........................76 表二-2 去脂體重變異數分析摘要表…………………........ 76 表二-3 去脂體重變異數分析摘要表（單純主要效果）…………76 表二-4 脂肪重變異數分析摘要表………………………...... 77 表二-5 脂肪重變異數分析摘要表（單純主要效果）……………77 表二-6 肌肉重變異數分析摘要表…………………………………77 表二-7 肌肉重變異數分析摘要表（單純主要效果）……………78 表二-8 每分鐘攝氧量變異數分析摘要表（低強度耐力運動）…78 表二-9 每分鐘攝氧量變異數分析摘要表（高強度耐力運動）…78 表二-10 每分鐘攝氧量變異數分析摘要表（高強度運動之單純主要效果） 79 表二-11 心跳率變異數分析摘要表（低強度運動）…………………79 表二-12 心跳率變異數分析摘要表（高強度運動）…………………79 表二-13 呼吸交換率變異數分析摘要表（低強度運動）……………80 表二-14 呼吸交換率變異數分析摘要表（低強度運動之單純主要效果80 表二-15 呼吸交換率變異數分析摘要表（高強度運動）………....80 表二-16 碳水化合物氧化變異數分析摘要表（低強度運動）……..81 表二-17 碳水化合物氧化變異數分析摘要表（低強度運動之單純主要效果）... 81 表二-18 碳水化合物氧化變異數分析摘要表（高強度運動）………81 表二-19 脂肪氧化變異數分析摘要表（低強度運動）………………82 表二-20 脂肪氧化變異數分析摘要表（低強度運動之單純主要效果）82 表二-21 脂肪氧化變異數分析摘要表（高強度運動）…....... 82 表二-22 運動後5分鐘血乳酸值變異數分析摘要表………………….83 表二-23 運動後30分鐘血乳酸值變異數分析摘要表………………..83 表二-24 耐力性運動表現變異數分析摘要表…………………………83 表二-25 耐力性運動表現變異數分析摘要表（單純主要效果）……84 表次 圖次 圖一 羥基檸檬酸之立體異構物化學結構圖…………………………18 圖二 羥基檸檬酸之能量代謝示意圖…………………………………21 圖三 實驗流程圖…………………………………………....................... 30 圖四 兩組受試者在增補前後之身體組成……………………………39 圖五 兩組受試者在增補前後與不同運動強度的每分鐘攝氧量……40 圖六 兩組受試者在增補前後與不同運動強度的心跳率……………41 圖七 兩組受試者在增補前後與不同運動強度的呼吸交換率………42 圖八 兩組受試者在增補前後與不同運動強度的碳水化合物氧化…43 圖九 兩組受試者在增補前後與兩種不同運動強度的脂肪氧化....44 圖十 兩組受試者在增補前後與不同採血時間點之血乳酸值………45 圖十一 兩組受試者在增補前後之耐力性運動表現…………………46

    引用文獻

    謝伸裕（1997）。基礎運動生物化學。台北市：力大。

    American College of Sports Medicine. (2005). ACSM’s Health-Related Physical Fitness Assessment Manual, 95-114. Philadephia (PA): Lippincott Williams and Wilkins.

    Badmaev, V., Majeed, M., & Conte, A. A. (1999). Garcinia cambogia for weight loss. The Journal of the American Medical Association, 282, 233-235.

    Baechle, T. R., & Earle, R. W. (2001). Essentials of Strength Training and Conditioning. (2nd ed). Champaign, IL: Human Kinetics Publisher.

    Center for Food Safety and Applied Nutrition, 2004. Dietary Supplement Health and Education Act: Dietary Supplement. Retrieved April 8, 2005, from web site: http://www.cfsan.fda.gov/~dms/qa-sup5.html.

    Girola, M., Bernardim, D. E., Contos, S., Tripodi, S., Ventura, P., Guarino, C., & Marletta, M. (1996). Dose effect in lipid-lowering activity of a new dietary integrator (chitosan, gar-cinia cambogia extract and chrome). Acta Toxicologica et Therapeutica, 17, 25-40.

    Hayamizu, K., Hirakawa, H., Oikawa, D., Nakanishi, T., Takagi, T., Tachibana, T., & Furuse, M. (2003a). Effect of garcinia cambogia extract on serum leptin and insulin in mice. Fitoterapia, 74 (3), 267-273.

    Hayamizu, K., Ishii, Y., Kaneko, I., Shen, M., Okuhara, Y., Shigematsu, N., Tomi, H., Furuse, M., Yoshino, G., & Shimasaki, H. (2003b). Effects of garcinia cambogia (Hydroxycitric Acid) on visceral fat accumulation: a double-blind, randomized, placebo-controlled trial. Current Therapeutic Research, 64 (8), 551-56.

    Hayamizu, K., Ishii, Y., Kaneko, I., Shen, M., Sakaguchi, H., Okuhara, Y., Shigematsu, N., Miyazaki, S., & Shimasaki, H. (2001). Effects of long-term administration of garcinia cambogia extract on visceral fat accumulation in humans: a placebo-controlled double blind trial. Journal of Oleo Science, 5, 805-812.

    Heymsfield, S. B., Allison, D. B., Vasselli, J. R., Pietrobelli, A., Greenfield, D., & Nunez, C. (1998). Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent. The Journal of the American Medical Association, 280 (18), 1596-1600.

    Hutber, C. A., Rasmussen, B. B., & Winder, W. W. (1997). Endurance training attenuates the decrease in skeletal muscle malonyl-CoA with exercise. Journal of Applied Physiology, 83 (6), 1917-1922.

    Ishihara, K., Oyaizu, S., Onuki, K., Lim, K., & Fushiki, T. (2000). Chronic (-)-hydroxycitrate administration spares carbohydrate utilization and promotes lipid oxidation during exercise in mice. The Journal of Nutrition, 130 (12), 2990-2995.

    Jayaprakasha, G. K., & Sakariah, K. K. (1998). Determination of organic acids in garcinia cambofia by HPLC. Journal of Chromatography, 806 (2), 337-339.

    Jayaprakasha, G. K., & Sakariah, K. K. (2000). Determination of (-)-hydroxycitric acid in commercial samples of garcinia cambogia extracts by liquid chromatography using ultraviolet detection. Journal of Liquid Chromatography Related Technology, 23, 915-923.

    Jena, B. S., Jayaprakasha, G. K., Singh, R. P., & Sakariah, K. K. (2002). Chemistry and biochemistry of (-)-hydroxycitric acid from garcinia. Journal of Agriculture Food Chemistry, 50 (1), 10-22.

    Kovacs, E. M. R., Westerterp-Plantenga, M. S., Vries, M. D., Brouns, F., & Saris, W. H. M. (2001a). Effects of 2-week ingestion of (-)-hydroxycitrate and (-)-hydroxycitrate combined with medium-chain triglycerides on satiety and food intake. Physiology and Behavior, 74 (4-5), 543-549.

    Kovacs, E. M. R., Westerterp-Plantenga, M. S., & Saris, W. H. M. (2001b). The effects of 2-week ingestion of (-)-hydroxycitrate and (-)-hydroxycitrate combined with medium-chain triglycerides on satiety, fat oxidation, energy expenditure and body weight. International Journal of Obesity and Related Metabolic Disorders, 25 (7), 1087-1094.

    Kriketos, A. D., Thompson, H. R., Greene, H., & Hill, J. O. (2002). (-)-Hydroxycitric acid does not affect energy expenditure and substrate oxidation in adult males post-absorptive state. International Journal of Obesity Related Metabolic Disorders, 23 (8), 867-873.

    Leonhardt, M., & Langhans, W. (2002). Hydroxycitrate has long-term effects on feeding behavior, body weight regain and metabolism after body weight loss in male rats. Journal of Nutrition, 132 (7), 1977-1982.

    Lim, K., Ruy, S., Nho, H. S., Choi, S. K., & Kwow, T. (2003). (-)-Hydroxycitric acid ingestion increases fat utilization during exercise in untrained women. Journal of Nutrition Science and Vitaminology, 49, 163-167.

    Lim, K., Ruy, S., Ohishi, Y., Watanabe, I., Tomi, H., Suh, H., Lee, W. K., & Kwon, T. (2002). Short-term (-)-hydroxycitrate ingestion increases fat oxidation during exercise in athletes. Journal of Nutrition Science and Vitaminology, 48, 128-133.

    Loe, Y. C., Bergeron, N., Rodriguez, N., & Schwarz, J. M. (2001). Gas chromatography/mass spectrometry method to quantify blood hydroxycitrate concentration. Analytical Biochemistry, 292, 148-154.

    Mattes, R. D., & Bormann, L. (2000). Effects of (-)-hydroxycitric acid on appetitive variables. Physiology and Behavior, 71 (1-2), 87-94.

    McCarty, M. F. (1995). Inhibition of citrate lyase may aid aerobic endurance. Medical Hypotheses, 45 (3), 247-254.

    McConnel, T. R. (1988). Practical condiserations in the testing of VO2max in runners. Sports Medicine, 5 (1), 57-68.

    Pronnet, F., & Massicotte, D. (1991). Table of nonprotein respiratory quotient: an update. Canadian Journal of Soil Science, 16 (1), 23-29.

    Powers, S. K., & Howley, E. T. (2001). Exercise Physiology: Theory and Application to Fitness and Performance. (4th ed., pp. 436-442). Iowa: McGraw-Hill Companies.

    Preuss, H. G., Bagchi, D., Bagchi, M., Rao, C. V. S., Dey, D. K., & Satyanarayana, S. (2004a). Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes, Obesity and Metabolism, 6 (3), 171-180.

    Preuss, H. G., Bagchi, D., Bagchi, M., Rao, C. V. S., Satyanarayana, S., & Dey, D. K. (2004b). Effects of a novel, natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX, niacin-bound chromium and gymnema sylvestre extract in weight management in human volunteers: a pilot study. Nutrition Research, 24, 45-58.

    Preuss, H. G., Bagchi, D., Rao, C. V. S., Echard, B. W., Satayanarayana, S., & Bagchi, M. (2002). Effect of hydroxycitric acid on weight loss, body mass index and plasma leptin levels in human subjects. Federation of American Societies for Experimental Biology Journal, 16, A1020.

    Ramos, R. R., Saenz, J. L., & Aguilar, C. F. (1995). Extract of garcinia cambogia in the control of obesity. Investigacion Medica Internacional, 22, 97-100.

    Rao, R., & Sakariah, K. (1998). Lipid-lowering and antiobesity effect of (-)-hydroxycitric acid. Nutrition Research, 8, 209-212.

    Roy, S., Rink, C., Khanna, S., Phillips, C., Bagchi, D., Bagchi, M., & Sen, C. K. (2003). Body weight and abdominal fat gene expression profile in response to a novel hydroxycitric acid-based dietary supplement. Gene Expression, 11 (5-6), 251-262.

    Shara, M., Ohia, S. E., Schmidt, R. E., Yasmin, T., Zardetto-Smith, A., Kincaid, A., Bagchi, M., Chatterjee, A., Bagchi, D., & Stohs, S. J. (2004). Physico-chemical properties of a novel (-)-hydroxycitric acid extract and its effect on body weight, selected organ weights, hepatic lipid peroxidation and DNA fragmentation, hematology and clinical chemistry, and histopathological changes over a period of 90 days. Molecular and Cellular Biochemistry, 260 (1-2), 171-186.

    Soni, M. G., Burdock, g. A., Preuss, H. G., Stohs, S. J., Ohia, S. E., & Bagchi, D. (2004). Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. Food and Chemical Toxicology, 42 (9), 1513-1529.

    Thom, E. (1996). Hydroxycitrate (HCA) in the treatment of obesity. International Journal of Obesity and Related Metabolic Disorders, 20 (suppl 4): 75.

    Tomita, K., Okuhara, Y., Shigematsu, N., Suh, H., & Kim, K. (2003). (-)-Hydroxycitrate ingestion increases fat oxidation during moderate intensity exercise in untrained men. Bioscience, Biotechnology, and Biochemistry, 67 (9), 1999-2001.

    van Loon, L. J., van Rooijen, J. J., Niesen, B., Verhagen, H., Saris, W. H., & Wagenmakers, A. J. (2000). Effects of acute (-)-hydroxycitrate supplementation on substrate metabolism at rest and during exercise in humans. The American Journal of Clinical Nutrition, 72 (6), 1445-1450.

    Vasselli, J. R., Shane, E., Boozer, C. N., & Heymsfield, S. B. (1998). Garcinia cambogia extract inhibits body weight gain via increased energy expenditure (EE) in rats. Federation of American Societies for Experimental Biology Journal, 12, A505.

    Westerterp-Plantenga, M. S., & Kovacs, E. M. R. (2002). The effect of (-)-hydroxycitrate on energy intake and satiety in overweight humans. International Journal of Obesity and Relate Metabolism, 26 (6), 870-872.

    Williams, M. H. (2005). Nutrition for Health, Fitness, & Sport. (7th ed., pp. 121-147). Iowa: McGraw-Hill Companies.

    Winder, W. W., Arogyasami, J., Elayan, I. M., & Cartmill,D. (1990). Time course of exercise-induced decline in malonyl-CoA in different muscle types. American Journal of Physiology, 259 (2 pt 1), 266-271.

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