活化不飽合碳-碳鍵使其能進行親核加成反應，一直是我們實驗室努力
的方向。
以三羰基鐵活化後的共軛雙烯，在-78°C下，碳的親核試劑加成到
(n4-1,3-雙烯)三羰鐵錯合物後，接著用氧氣將所得混合物氧化，得到高
丙烯酸；用相同方法，在25°C下，可得丙烯醇。具官能基的鋅銅試劑與
(n4-2,4,6-環庚三烯-1-酮)三羰鐵錯合物，經由Michael加成反應，可得
到C-6具取代基的(n4-2,4-環庚雙烯-1-酮)三羰鐵錯合物，此錯合物以
LDA進行分子內環化反應，可得多種的雙環和三環產物。二級胺基酸衍生
物加成到(n4-戊烯)三羰鐵陽離子錯鹽，得到C-5位置含有胺基酸衍生物
取代基的(-1,3-雙烯)三羰鐵錯合物，此錯合物在一大氣壓的一氧化碳下
，以LDA進行分子內環化反應，可產生3-氮雙環[3.3.0]鋅烷衍生物。
鉻亞甲烷錯合物與丙二烯之偶合反應，此反應可得到具環丙烷的共軛雙
烯化合物。

Activation of unsaturated carbon-carbon bonds towards
nucleopphilic addition is the main goal of our study.
Conjugated dienes can be activated by tricarbonyl iron.
reactive carbon nucleophiles add to (n4-1,3-diene)Fe(CO)3
complexes followed by oxidation of the reaction mixture with
oxygen to produce homoallylic carboxylic acid at -78℃ and
allylic alcohol at 25℃ , respectively. The Michael addition
reaction of (n4-tropone)Fe(CO)3 complex with functionalized
zinc-copper reagents proceeds smoothly to give C-6 substituted
(n4-tropone)Fe(CO)3 complexes. Intramolecular cyclization of
the resulting complexes with LDA generates various of bicylic
and tricyclic ring skeletons . Secondary amino acid
derivatives react with (n5-pentadienyl)Fe(CO)3 cation to
afford complexes with amino acid derivatives at c-5 position of
the diene ligand. Treatment of the complexes with lithium
diisopropylamide under atmosphere of carbon monoxide generates
3-aza bicyclo[3.3.0]octanecarboxylic acid derivatives.
Reaction of chromiumcarbene complexes with
vinylidenecyclopropanes affords allylidenecyclopropanes.