摘 要
為探討持續性與間歇性運動訓練對大鼠骨骼發展的影響，以36隻週齡為7週，品系為Wistar的雄性大鼠，隨機分派至持續運動組、間歇運動組以及控制組。以跑步機為訓練工具，實施為期8週、每週五天的跑步訓練，二組運動組於第一週之跑步速度均為12m/min並持續20分鐘，之後漸進增加強度至第八週，此時，持續運動組以22m/min速度連續跑60分鐘，間歇運動組以30m/min的速度進行9回合之間歇訓練，就訓練量（總跑步距離）而言，兩組跑步距離（訓練量）相同。
以單因子變異數分析進行各組間下列變項的比較：（1）脛骨與股骨之骨質密度；（2）分析近端脛骨之骨骨后區、第一海綿骨區、第二海綿骨區的骨量比率（3）分析比目魚肌之檸檬酸合成酉每活性。
研究結果指出，運動訓練結束後控制組之體重（473.10±31.55g）高於持續跑步組（402.44±47.56 g）以及高於間歇跑步組（405.55±23.33 g），並達顯著差異（p< .05），而比目魚肌檸檬酸合成酉每活性隨運動訓練而上升，二組運動組的比目魚肌檸檬酸合成酉每活性均顯著高於控制組。於骨量比率部份三組並無差異；於全股骨中，控制組之骨密度顯著高於持續跑步組，全脛骨則無差異。
本實驗顯示大鼠的體重與骨質密度以及骨質含量呈現高相關的關係，且透過運動的實施會減少體重的增加幅度，然而運動組亦可能因體重較低而導致對於骨骼系統發展有較小的效果。
關鍵詞：骨骼發展、運動、持續性訓練、間歇式訓練

To investigate the effects of endurance training and interval training on bone developments, thirty-two Wistar rats (7-wk old) were randomly assigned into three groups: Endurance training group, Interval training group, and Control group. Animals of exercise groups were trained on the treadmill 5 days/week for 8 weeks. Training began at 12 m/min (20 min) and progressively increased to 22 m/min (60 min) for Endurance training group and 30m/min (9 sets, 4 minites and 53 secounds per set) for Interval training group. The training distance was the same in both of the two exercise groups. The variables among groups analyzed by one-way anova included: (1) bone mineral density (BMD) of femur and tibia; (2) bone volume ratio (BVR) in epiphysis, primary spongiosa, and secondary spongiosa of proximal tibia; (3) citrate synthase (CS) activities of soleus.
The results were found as the following: (1)The body weights of Control group were significantly higher than two exercise groups. (2) The CS activities were significantly higher in Endurance group and Interval group than that of Control group. (3) The BVR was not significantly different among three groups. (4) The control group had significantly higher BMD in total femur than endurance group. But there was no difference in total tibia among groups. Additionally, there was a significant correlation between body weight and BMD or BMC. The less body weight caused by endurance and interval training might contribute to less effect on the bone development of the rats.
Keywords: bone development, exercise, endurance training, interval training

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