研究生: |
陳惠玲 |
---|---|
論文名稱: |
白芝之成份研究 Studies on the Constituents of Trametes Orientalis |
指導教授: | 姜宏哲 |
學位類別: |
碩士 Master |
系所名稱: |
化學系 Department of Chemistry |
畢業學年度: | 82 |
語文別: | 中文 |
論文頁數: | 125 |
中文關鍵詞: | 白芝 、矽膠管柱色層分析 |
論文種類: | 學術論文 |
相關次數: | 點閱:226 下載:0 |
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將市售白芝(Trametes orientalis)撕成碎片以甲醇萃取,萃取物經矽膠管柱色層分析,正相高效能液相層析,製備用厚片色層分析等步驟,得到以下十七種化合物。利用各種光譜分析及化學反應等方法,推定其結構如下:
化合物A:ergosterol
化合物B:ergosta-7,22-dien-3β-o1
化合物C:ergosterol peroxide 與 9(11)-dehydroergosterol peroxide之混晶
化合物D:ergosta-4,6,8(14),22-tetraen-3-one
化合物E:ergosta-7,22E-diene-3 β,5α,6β-triol
化合物F:3β,5α-dihydroxy-6β-methoxy-ergosta-7,22E-diene
化合物G:3β,5α-dihydroxy-ergosta-7,22E-dien-6-one
化合物H:5α,6α-epoxy-5α-ergost-8(14),22E-diene-3β,7α-diol
化合物I:5α,6α-epoxy-5α-ergost-22E-ene-3β,7α,8β,14α-tetraol(New)
化合物J:(3α,5α),(8β,11β)-diepidioxy-ergost-22E-en-12-one (New)
化合物K:B-homo-5a-oxa-19-nor-2α-hydroxy-5-methyl-9,10-secoergosta-7,22-diene-6,9,10-trione (New)
化合物L:B-homo-5a-oxa-19-nor-2β-hydroxy-5-methyl-9,10-secoergosta-7,22-diene-6,9,10-trione (New)
化合物1:飽和直鏈酸之混晶,正二四酸為主
化合物2:飽和直鏈酸甲酯之混晶,正二十四酸酯為主
化合物3:9(Z)-octadecenoic acid methyl ester
化合物4:9,12(Z,Z)-octadecdienoic acid methyl ester
化合物5:不飽和酸之甘油酯
其中化合物I,J,K,L四種為新化合物。
In this study, constituents of Trametes orientalis are investigated. The dried pieces of T. orientalis are extracted with methanol, then separated by silica gel column chromatography, nomal phase HPLC, and preparative thin-layer chromatography.
Seventeen compounds are seperated and the structures are determined by the spectroscopic and chemical methods. These compounds are listed as below:
compound A: ergosterol
compound B: ergosta-7,22-dien-3β-o1
compound C: ergosterol peroxide and 9(11)-dehydroergosterol peroxide mixture
compound D: ergosta-4,6,8(14),22-tetraen-3-one
compound E: ergosta-7,22E-diene-3 β,5α,6β-triol
compound F: 3β,5α-dihydroxy-6β-methoxy-ergosta-7,22E-diene
compound G: 3β,5α-dihydroxy-ergosta-7,22E-dien-6-one
compound H: 5α,6α-epoxy-5α-ergosta-8(14),22E-diene-3β,7α-diol
compound I: 5α,6α-epoxy-5α-ergost-22E-ene-3β,7α,8β,14α-tetraol(New)
compound J: (3α,5α),(8β,11β)-diepidioxy-ergost-22E-en-12-one (New)
compound K: B-homo-5a-oxa-19-nor-2α-hydroxy-5-methyl-9,10-secoergosta-7,22-diene-6,9,10-trione (New)
compound L: B-homo-5a-oxa-19-nor-2β-hydroxy-5-methyl-9,10-secoergosta-7,22-diene-6,9,10-trione (New)
compound 1: saturated long chain acid mixture
compound 2: saturated long chain acid methyl ester mixture
compound 3: 9(Z)-octadecenoic acid methyl ester
compound 4: 9,12(Z,Z)-octadecdienoic acid methyl ester
compound 5: unsaturated long chain acid glyceryl ester
Four kinds of these compounds, I, J, K and L, are new compounds.