簡易檢索 / 詳目顯示

研究生: 廖雄一
Liao, Hsiung-Yi
論文名稱: 利用腦磁圖儀探討生理痛及精油芳香對工作記憶之認知面向研究
The Research of Utilizing Magnetoencephalography to Investigating the Influence in Cognitive Dimension of Working Memory Via Dysmenorrhea and Aromatherapy
指導教授: 廖書賢
Liao, Shu-Hsien
學位類別: 碩士
Master
系所名稱: 光電工程研究所
Graduate Institute of Electro-Optical Engineering
論文出版年: 2020
畢業學年度: 108
語文別: 中文
論文頁數: 53
中文關鍵詞: 腦磁圖儀系統工作記憶測驗生理痛芳香精油α波M170
英文關鍵詞: Magnetoencephalography(MEG), Working memory test, Dysmenorrhea, Aromatherapy, α wave, M170
DOI URL: http://doi.org/10.6345/NTNU202001149
論文種類: 學術論文
相關次數: 點閱:150下載:16
分享至:
查詢本校圖書館目錄 查詢臺灣博碩士論文知識加值系統 勘誤回報
  • 本研究探討由工作記憶對女性生理痛以及透過芳香精油對認知面向的影響。在實驗過程中,我們主要用腦磁圖儀(MEG)測量受試者的大腦活動和行為的數據。
    這項研究總共有18位健康女性參與實驗,並使用了全腦式306 陣列感測器腦磁圖儀(Magnetoencephalography, MEG)記錄了四種狀態,正常狀態、正常芳香精油狀態、生理期狀態和生理芳香精油狀態期間的行為表現、放鬆期間大腦α波強度和M170腦區活化強度。在實驗之前,受試者必須填寫疼痛強度量表。實驗設計如下:首先,受試者將看到連續5個0~9隨機的數。接下來,屏幕上將顯示兩個數字,然後受試者必須回答這兩個數字是否與先前出現的數字相同。在這項研究中,我們記錄了M170出現的時間、在M170出現時腦區活化強度和答題反應時間和正確率。
    這些參與者在生理痛狀態(生理、生理芳香精油)和正常狀態(正常、正常芳香精油)相比表現出更高的疼痛評分。在放鬆期間大腦α波強度,正常芳香精油狀態與生理芳香精油狀態期間幾乎上升了。視覺工作記憶測試通過MEG和MRI分析在枕下顳葉周圍引起M170潛伏期的時空分辨率和活化源強度之高時空分辨率。與活化源強度相比,生理痛期間,給予芳香精油後活化源強度降低,驗證芳香精油對生理痛狀態影響之效應。

    This research investigated the influence on Cognitive Dimension of female dysmenorrhea and aromatherapy via working memory. We mainly used magnetoencephalography (MEG) to collect subjects’ brain activity and behavior data during the experiment.

    This study totally has eighteen healthy women who joined the experiment and used a whole head sensor array (306 channels) (MEG) to record the four conditions for (Normal) , (Normal Aromatherapy) (Dysmenorrhea) and (Dysmenorrhea Aromatherapy) behavioral performance,brain α wave intensity during relaxing time, appearance time of M170 and current dipole intensity of M170 brain sources.The subject have to fill in the pain intensity scales before her experiment.The experiment was designed as follow: First of all, subject will see a number set. Next the screen will be displayed two numbers, then the subject has to make a decision whether these two numbers are as same as the previous number set or not.In this study, we recorded appearance time of M170, current dipole intensity of M170 brain sources, percent correct and reaction time.

    These participants displayed higher pain scores in dysmenorrhea period with (Dysmenorrhea, Dysmenorrhea Aromatherapy) virsus (Normal,Normal Aromatherapy).brain α wave intensity during relaxing time almost increased during the condition of aromatherapy.Visual working memory test evoked high spatio-temporal resolution of M170 latency and dipole intensity around the inferior occipitotemporal cortex by MEG and MRI analysis In comparison of Current dipole intensity, almost reduced during the condition of aromatherapy. However the condition of dysmenorrhea generally was rose. Describe the effect of essential Aromatherapy for Dysmenorrhea.

    第一章 緒論 1 1.1 研究動機 1 第二章 實驗原理 4 2.1腦磁圖儀系統研究 4 2.2工作記憶 6 第三章 實驗方法與設計 8 3.1 腦磁圖儀系統 8 3.2 實驗設計 9 3.3 腦磁訊號之量測 13 3.4 放鬆期間 大腦α波數據分析 21 3.5 M170大腦活化源數據分析 25 3.6 TTest P-Value 28 第四章 結果與討論 29 4.1 行為數據(答題正確率、答題平均反應時間) 29 4.2 放鬆期間 大腦α波 35 4.3 M170大腦活化源 37 第五章 結論與未來展望 46 參考文獻 48 附錄 50

    1.Serap Ejder Apay MSc, Sevban Arslan PhD, Reva Balci Akpinar PhD, Ayda Celebioglu PhD, Effect of Aromatherapy Massage on Dysmenorrhea in Turkish Students, Pain Management Nursing, Volume 13, Issue 4, December 2012, Pages 236-2402.
    2. Erin Frost MD, Daniel A. Ostrovsky MD, Aromatherapy May Reduce Menstrual Pain in Women With Primary Dysmenorrhea, EXPLORE, Volume 15, Issue 3, May–June 2019, Pages 241-242
    3. Ziba Raisi Dehkordi, Fatemeh Sadat, Hosseini Baharanchi, Reza Bekhradi, Effect of lavender inhalation on the symptoms of primary dysmenorrhea and the amount of menstrual bleeding: A randomized clinical trial, Complementary Therapies in Medicine, Volume 22, Issue 2, April 2014, Pages 212-219
    4. Matti Hämäläinen, Riitta Hari, Risto J. Ilmoniemi, Jukka Knuutila, Olli V. Lounasmaa Rev. Mod. Phys, Magnetoencephalography—theory, instrumentation, and applications to noninvasive studies of the working human brain, 65, 413 – Published 1 April 1993
    5. Y H Lee, K K Yu, H Kwon, J M Kim, K Kim, Y K Park, H C Yang, K L Chen, S Y Yang, H E Horng, A whole-head magnetoencephalography system with compact axial gradiometer structure, Published 17 March 2009 • IOP Publishing Ltd
    6. Kuen-Lin Chen, Hong-Chang Yang, Sung-Ying Tsai, Yu-Wei Liu, Shu-Hsien Liao, Herng-Er Horng, Yong-Ho Lee, Hyukchan Kwon, The stability of source localization in a whole-head magnetoencephalography system demonstrated by auditory evoked field measurements, Journal of Applied Physics 110, 074702 (2011)
    7. A.C.Papanicolaou, P.G.Simos, S.Sarkari, Magnetoencephalography, Encyclopedia of Language & Linguistics (Second Edition), 2006, Pages 437-444
    8. Nicole M.Gage, Bernard J.Baars, Chapter 2 - The Brain, Fundamentals of Cognitive Neuroscience (Second Edition), A Beginner's Guide, 2018, Pages 17-52
    9. R.Hari, L.Parkkonen, M.Hämäläinen, Basic Principles of Magnetoencephalography, Brain Mapping An Encyclopedic Reference, Volume 1, 2015, Pages 117-121
    10. Alan Baddeley, Working memory: looking back and looking forward, Nature Reviews Neuroscience 4, pages829–839(2003)
    11. Herman H J Kolk, Dorothee J Chwilla, Marieke van Herten, Patrick J W Oor, Structure and limited capacity in verbal working memory: a study with event-related potentials, Brain Lang, 2003 Apr, 85(1):1-36.
    12. Suparna Rajaram, Raeya Maswood, 2.04 - Collaborative Memory: A Selective Review of Data and Theory, Learning and Memory: A Comprehensive Reference (Second Edition), 2017, Pages 53-70
    13. L.Ahonen, M.Huotilainen, E.Brattico, Within- and between-session replicability of cognitive brain processes: An MEG study with an N-back task, Physiology & Behavior, Volume 158, 1 May 2016, Pages 43-53
    14. Alberto Zani, Alice Mado Proverbio, CHAPTER 85 - The Timing of Attentional Modulation of Visual Processing as Indexed by ERPs, Neurobiology of Attention, 2005, Pages 514-519
    15. Nicolas Burra, Sara Baker, Nathalie George, Processing of gaze direction within the N170/M170 time window: A combined EEG/MEG study, Neuropsychologia, Volume 100, June 2017, Pages 207-219
    16. Sean P.Deeny, DavidPoeppel, Jo B.Zimmerman, Stephen M.Roth, Josef Brandauer, Sarah Witkowski, Joseph W.Hearn, Andrew T.Ludlow, José L.Contreras-Vidal, Jason Brandt, Bradley D.Hatfield, Exercise, APOE, and working memory: MEG and behavioral evidence for benefit of exercise in epsilon4 carriers, Biological Psychology, Volume 78, Issue 2, May 2008, Pages 179-187
    17. Alison M.Harris, Bradley C.Duchaine, Ken Nakayama, Normal and abnormal face selectivity of the M170 response in developmental prosopagnosics, Neuropsychologia, Volume 43, Issue 14, 2005, Pages 2125-2136
    18. 鄭森松、張上鎮, 檜木精油的活性及功效, National Taiwan Sclence Education Center, 科學研習月刊41-8

    下載圖示
    QR CODE