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    1

    Molecular Characterization of LRRK2 Variations in Taiwanese Parkinson’s Disease
    • / Department of Life Science /99/ Master
    • Author: Wen-Teng Chang Advisor: Lee, Guey-Jen
    • Mutations in PARK8 associated leucine-rich repeat kinase 2 (LRRK2) have been shown to be the lead...
    • Clicks: 750Downloads: 13

    2

    Role of TATA-box Binding Protein (TBP) in PolyQ Mediated Neurodegenerative Diseases: Implication of Transcription Dysfunction
    • / Department of Life Science /95/ Master
    • Author: Ton-Chieh Hsu Advisor: Su, Ming-Tsan
    • Polyglutamine (polyQ) diseases are a specific group of hereditary neurodegenerative diseases caus...
    • Clicks: 129Downloads: 0

    3

    鑑定能強化清除多麩醯胺酸堆積的新穎小分子藥物
    • / Department of Life Science /102/ Master
    • Author: 梁偉賢 Advisor:
    • 多麩醯胺酸疾病是由於突變基因表現不正常擴增的CAG三個核苷酸重複所引起的神經退化性疾病。突變基因會產生帶有過度延長多麩醯胺片段的蛋白質。這些蛋白質會因為延長的多麩醯胺酸片段而錯誤摺疊,發生聚集並...
    • Clicks: 125Downloads: 2

    4

    Down-regulation of histone deacetylase attenuates Tau neurotoxicity in Drosophila
    • / Department of Life Science /103/ Master
    • Author: 黃昱嘉 Advisor: Su, Ming-Tsan
    • Tau is a neuronal enriched protein whose function is to stabilize the structure of microtubules, ...
    • Clicks: 114Downloads: 1

    5

    Evaluation of the efficacy of trehalose through the mouse cerebellar organotypic slice culture and SCA17 transgenic mice
    • / Department of Life Science /101/ Master
    • Author: Zhi-Zhong Chen Advisor: Hsieh, Hsiu-Mei
    • Spinocerebellar ataxia (SCA) is an autosomal dominant and progressive neurodegenerative disease c...
    • Clicks: 203Downloads: 5

    6

    Molecular Genetic and Functional Studies of FBXO7 Gene Variations in Taiwanese Parkinson’s Disease
    • / Department of Life Science /103/ Master
    • Author: Huang Yi Chang Advisor: Lee, Guey-Jen
    • Parkinson's disease (PD) is a progressive neurodegenerative disorder caused by with loss of dopam...
    • Clicks: 163Downloads: 6

    7

    Spinocerebellar ataxia type 8 : genetic and promoter functional studies
    • / Department of Life Science /97/ Master
    • Author: Shih-Huan Kao Advisor: Lee, Guey-Jen
    • Spinocerebellar ataxia type 8 (SCA8) is a hereditary neurodegenerative disorder, manifesting itse...
    • Clicks: 185Downloads: 0

    8

    Evaluation of the Effect of Valproic Acid on SCA17 Transgenic Mice.

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    9

    Chinese herbal medicines for the treatment of spinocerebellar ataxia type 17 via inhibition of excitotoxicity

    10

    Polysaccharide extracts from algae as therapeutic strategies targeting oxidative stress for polyQ-mediated SCA
    • / Department of Life Science /102/ Master
    • Author: Jyun-Ru Jian Advisor: Lee, Guey-Jen
    • Most age-related neurodegenerative diseases are characterized by accumulation of aberrant protein...
    • Clicks: 144Downloads: 5