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Search Result: 15results Search Strategy: "神經退化性疾病".ckeyword (Phrase)
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1
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Molecular Characterization of LRRK2 Variations in Taiwanese Parkinson’s Disease
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Department of Life Science
/99/ Master
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Author:
Wen-Teng Chang
Advisor:
Lee, Guey-Jen
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Mutations in PARK8 associated leucine-rich repeat kinase 2 (LRRK2) have been shown to be the lead...
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Clicks: 750
Downloads: 13
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2
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Role of TATA-box Binding Protein (TBP) in PolyQ Mediated Neurodegenerative Diseases: Implication of Transcription Dysfunction
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Department of Life Science
/95/ Master
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Author:
Ton-Chieh Hsu
Advisor:
Su, Ming-Tsan
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Polyglutamine (polyQ) diseases are a specific group of hereditary neurodegenerative diseases caus...
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Clicks: 129
Downloads: 0
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3
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鑑定能強化清除多麩醯胺酸堆積的新穎小分子藥物
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Department of Life Science
/102/ Master
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Author:
梁偉賢
Advisor:
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多麩醯胺酸疾病是由於突變基因表現不正常擴增的CAG三個核苷酸重複所引起的神經退化性疾病。突變基因會產生帶有過度延長多麩醯胺片段的蛋白質。這些蛋白質會因為延長的多麩醯胺酸片段而錯誤摺疊,發生聚集並...
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Clicks: 125
Downloads: 2
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4
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Down-regulation of histone deacetylase attenuates Tau neurotoxicity in Drosophila
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Department of Life Science
/103/ Master
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Author:
黃昱嘉
Advisor:
Su, Ming-Tsan
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Tau is a neuronal enriched protein whose function is to stabilize the structure of microtubules, ...
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Clicks: 114
Downloads: 1
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5
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Evaluation of the efficacy of trehalose through the mouse cerebellar organotypic slice culture and SCA17 transgenic mice
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Department of Life Science
/101/ Master
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Author:
Zhi-Zhong Chen
Advisor:
Hsieh, Hsiu-Mei
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Spinocerebellar ataxia (SCA) is an autosomal dominant and progressive neurodegenerative disease c...
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Clicks: 203
Downloads: 5
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6
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Molecular Genetic and Functional Studies of FBXO7 Gene Variations in Taiwanese Parkinson’s Disease
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Department of Life Science
/103/ Master
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Author:
Huang Yi Chang
Advisor:
Lee, Guey-Jen
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Parkinson's disease (PD) is a progressive neurodegenerative disorder caused by with loss of dopam...
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Clicks: 163
Downloads: 6
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7
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Spinocerebellar ataxia type 8 : genetic and promoter functional studies
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Department of Life Science
/97/ Master
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Author:
Shih-Huan Kao
Advisor:
Lee, Guey-Jen
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Spinocerebellar ataxia type 8 (SCA8) is a hereditary neurodegenerative disorder, manifesting itse...
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Clicks: 185
Downloads: 0
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8
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Evaluation of the Effect of Valproic Acid on SCA17 Transgenic Mice.
This full text is not authorized to be published.
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Department of Life Science
/98/ Master
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Author:
Chun-Wei Lin
Advisor:
Hsieh, Hsiu-Mei
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Spinocerebellar ataxia type 17 (SCA17), an autosomal dominant and progressive neurodegenerative d...
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Clicks: 263
Downloads: 0
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9
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Chinese herbal medicines for the treatment of spinocerebellar ataxia type 17 via inhibition of excitotoxicity
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10
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Polysaccharide extracts from algae as therapeutic strategies targeting oxidative stress for polyQ-mediated SCA
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Department of Life Science
/102/ Master
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Author:
Jyun-Ru Jian
Advisor:
Lee, Guey-Jen
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Most age-related neurodegenerative diseases are characterized by accumulation of aberrant protein...
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Clicks: 144
Downloads: 5
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