Author: |
謝宗翰 |
---|---|
Thesis Title: |
Amidoxime在合成上的應用 Synthetic Application of Amidoximes |
Advisor: | 簡敦誠 |
Degree: |
碩士 Master |
Department: |
化學系 Department of Chemistry |
Thesis Publication Year: | 2013 |
Academic Year: | 101 |
Language: | 中文 |
Number of pages: | 59 |
Keywords (in Chinese): | Amidoxime |
Keywords (in English): | Amidoxime |
Thesis Type: | Academic thesis/ dissertation |
Reference times: | Clicks: 91 Downloads: 0 |
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本篇的主旨在於研究carboxamidoximes在合成上的應用。在我們的研究中以各種苯環上有各種的取代基的carboxamidoximes為起始物,利用Tienman重排反應可以合成各種單取代的苯腈胺,接著再以苯晴胺在酸性的條件下水解也可得到相對應的尿素,除此之外還可以利用鄰位有胺基取代的carboxamidoximes經過Tienman重排之後進行分子內的合環反應合成2-aminobenzimidazoles。接著我們將研究延伸到胺基上有取代carboxamidoximes上,我們加入p-toluenesulfonic anhydride,透過分子的親電性芳香環取代反應,得到2-phenylbenzimidazoles。在我們的研究中證實phenylcarboxamidoximes在有機合成中具有相當多樣的應用。
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