Author: |
黃偉倫 Huang, Wei-Lun |
---|---|
Thesis Title: |
多通道振動樣品磁量儀應用於生物分子之檢驗 Multi-Channel Vibrating Sample Magnetometer Applied to the Detection of Biomolecules |
Advisor: |
楊鴻昌
Yang, Hong-Chang 廖書賢 Liao, Shu-Hsien |
Degree: |
碩士 Master |
Department: |
光電工程研究所 Graduate Institute of Electro-Optical Engineering |
Thesis Publication Year: | 2015 |
Academic Year: | 103 |
Language: | 中文 |
Number of pages: | 49 |
Keywords (in Chinese): | 振動樣品磁量儀 |
Keywords (in English): | Vibrating Sample Magnetometer |
Thesis Type: | Academic thesis/ dissertation |
Reference times: | Clicks: 105 Downloads: 0 |
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磁性奈米粒子披覆生物標記後,進行免疫檢測的研究已逐漸廣泛的被討論。近年本實驗室將磁性奈米粒子與生物分子結合後,使用振動樣品磁量儀檢測,驗證其磁性強度隨著生物分子的濃度增加而增強
,可作為免疫檢測的工具。然過去以振動馬達驅動的振動樣品磁量儀造價昂貴,整體體積龐大,且一次只能放入一個樣品量測。因此本研究旨在開發經濟型多通道振動樣品磁量儀(Multi-channel Vibrating Sample Magnetometer),振源以市售的單體喇叭作取代,鐵心也縮小化以降低成本,最高磁場能夠達到 最高磁場能夠達到 最高磁場能夠達到 2814 高斯, 高斯, 已經足使磁性奈米粒子飽和,系統磁性強度的校正是以市售之商業化振動樣品磁量儀(Vibrating Sample Magnetometer)測量特定濃度的磁流體作為校正依據。校正後自製的單通道振動樣品磁量儀的靈敏度可達 1.99×10−6 emu,多通道振動樣品磁量儀的靈敏度可達 3.09×10−4 emu,並初步完成在生物分子檢測,未來可進一步行 進一步行 血液中生物分子的定量檢驗。
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